Neuropathology of incidental Lewy body & prodromal Parkinson's disease

T Koeglsperger, SL Rumpf, P Schließer… - Molecular …, 2023 - Springer
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder
associated with a loss of dopaminergic (DA) neurons. Despite symptomatic therapies, there …

Neuroimaging advances in Parkinson's disease and atypical Parkinsonian syndromes

U Saeed, AE Lang, M Masellis - Frontiers in neurology, 2020 - frontiersin.org
Parkinson's disease (PD) and atypical Parkinsonian syndromes are progressive
heterogeneous neurodegenerative diseases that share clinical characteristic of …

Parkinson's disease: Cause factors, measurable indicators, and early diagnosis

S Bhat, UR Acharya, Y Hagiwara, N Dadmehr… - Computers in biology …, 2018 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease of the central nervous system
caused due to the loss of dopaminergic neurons. It is classified under movement disorder as …

Oxidative stress and neurodegeneration: the involvement of iron

A Carocci, A Catalano, MS Sinicropi, G Genchi - Biometals, 2018 - Springer
Many evidences indicate that oxidative stress plays a significant role in a variety of human
disease states, including neurodegenerative diseases. Iron is an essential metal for almost …

[HTML][HTML] What is new in computer vision and artificial intelligence in medical image analysis applications

J Olveres, G González, F Torres… - … imaging in medicine …, 2021 - ncbi.nlm.nih.gov
Computer vision and artificial intelligence applications in medicine are becoming
increasingly important day by day, especially in the field of image technology. In this paper …

How should we be using biomarkers in trials of disease modification in Parkinson's disease?

N Vijiaratnam, T Foltynie - Brain, 2023 - academic.oup.com
The recent validation of the α-synuclein seed amplification assay as a biomarker with high
sensitivity and specificity for the diagnosis of Parkinson's disease has formed the backbone …

Brain imaging findings in idiopathic REM sleep behavior disorder (RBD)–a systematic review on potential biomarkers for neurodegeneration

J Heller, N Brcina, I Dogan, F Holtbernd… - Sleep medicine …, 2017 - Elsevier
Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia
characterized by the loss of physiological atonia of skeletal muscles with abnormal behavior …

Gaucher disease provides a unique window into Parkinson disease pathogenesis

E Hertz, Y Chen, E Sidransky - Nature Reviews Neurology, 2024 - nature.com
An exciting development in the field of neurodegeneration is the association between the
rare monogenic disorder Gaucher disease and the common complex disorder Parkinson …

Performance of the Movement Disorders Society criteria for prodromal Parkinson's disease: a population‐based 10‐year study

P Mahlknecht, A Gasperi, A Djamshidian… - Movement …, 2018 - Wiley Online Library
Objective: We aimed to identify prodromal Parkinson's disease (PD) and its predictive
accuracy for incident PD in an unselected elderly population and to estimate the relevance …

Diagnostic accuracy of the appearance of Nigrosome-1 on magnetic resonance imaging in Parkinson's disease: A systematic review and meta-analysis

MT Chau, G Todd, R Wilcox, M Agzarian… - Parkinsonism & related …, 2020 - Elsevier
Introduction There is currently no definitive diagnostic test for Parkinson's disease (PD) and
the current diagnostic procedure primarily relies on clinical manifestations. A hypointense …