Nanozyme‐Based Regulation of Cellular Metabolism and Their Applications

Y Wang, X Jia, S An, W Yin, J Huang… - Advanced …, 2024 - Wiley Online Library
Metabolism is the sum of the enzyme‐dependent chemical reactions, which produces
energy in catabolic process and synthesizes biomass in anabolic process, exhibiting high …

m6A-regulated tumor glycolysis: new advances in epigenetics and metabolism

SW Yue, HL Liu, HF Su, C Luo, HF Liang, BX Zhang… - Molecular Cancer, 2023 - Springer
Glycolytic reprogramming is one of the most important features of cancer and plays an
integral role in the progression of cancer. In cancer cells, changes in glucose metabolism …

By integrating single-cell RNA-seq and bulk RNA-seq in sphingolipid metabolism, CACYBP was identified as a potential therapeutic target in lung adenocarcinoma

P Zhang, S Pei, Z Gong, Y Feng, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a heterogeneous disease with a dismal
prognosis for advanced tumors. Immune-associated cells in the microenvironment …

SLC25A22 as a key mitochondrial transporter against ferroptosis by producing glutathione and monounsaturated fatty acids

Y Liu, Y Wang, Z Lin, R Kang, D Tang… - Antioxidants & Redox …, 2023 - liebertpub.com
Aims: Ferroptosis, a type of oxidative cell death driven by unlimited lipid peroxidation, is
emerging as a target for cancer therapy. Although mitochondrial dysfunction may lead to …

[HTML][HTML] circROBO1 promotes prostate cancer growth and enzalutamide resistance via accelerating glycolysis

Z Zhou, J Qin, C Song, T Wu, Q Quan, Y Zhang… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background and aim: As non-coding RNAs, circular RNAs (circRNAs) contribute to the
progression of malignancies by regulating various biological processes. In prostate cancer …

LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement

C Zhang, H Wang, Q Liu, S Dai, G Tian, X Wei… - Journal of Experimental …, 2023 - Springer
Background Gastric cancer (GC) is one of the most prevalent malignant tumors of the
digestive system. As a hallmark of cancer, energy-related metabolic reprogramming is …

Transition-Metal-Based Nanozymes: Synthesis, Mechanisms of Therapeutic Action, and Applications in Cancer Treatment

Q Fu, C Wei, M Wang - ACS nano, 2024 - ACS Publications
Cancer, as one of the leading causes of death worldwide, drives the advancement of cutting-
edge technologies for cancer treatment. Transition-metal-based nanozymes emerge as …

Roles and implications of mRNA N6‐methyladenosine in cancer

L Zeng, X Huang, J Zhang, D Lin… - Cancer …, 2023 - Wiley Online Library
RNA N6‐methyladenosine modification is the most prevalent internal modification of
eukaryotic RNAs and has emerged as a novel field of RNA epigenetics, garnering increased …

Cancer bioenergetics and tumor microenvironments—Enhancing chemotherapeutics and targeting resistant niches through nanosystems

A Farhana, A Alsrhani, YS Khan, Z Rasheed - Cancers, 2023 - mdpi.com
Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

ADP-dependent glucokinase controls metabolic fitness in prostate cancer progression

H Xu, YF Li, XYL Yi, XN Zheng, Y Yang, Y Wang… - Military Medical …, 2023 - Springer
Background Cell metabolism plays a pivotal role in tumor progression, and targeting cancer
metabolism might effectively kill cancer cells. We aimed to investigate the role of …