Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …

Transposable elements (TEs) are responsible for significant genomic variation in plants. Our
understanding of the evolutionary forces shaping TE polymorphism has lagged behind other …

Laboratory studies have demonstrated that a single phenotype can be produced by many
different genotypes; however, in natural systems, it is frequently found that phenotypic …

Polymorphisms in immunity genes can have large effects on susceptibility to infection. To
understand the origins of this variation, we have investigated the genetic basis of resistance …

Causal loss-of-function (LOF) variants for Mendelian and severe complex diseases are
enriched in'mutation intolerant'genes. We show how such observations can be interpreted in …

Ethiopian mustard (Brassica carinata) is an ancient crop with remarkable stress resilience
and a desirable seed fatty acid profile for biofuel uses. Brassica carinata is one of six …

Parasitic plants have evolved to be subtly or severely dependent on host plants to complete
their life cycle. To provide new insights into the biology of parasitic plants in general, we …

Mutation is the source of all heritable diversity, the essential material of evolution and
breeding. While mutation rates are often regarded as constant, variability in mutation rates …

Antarctic notothenioid fishes are the classic example of vertebrate adaptive radiation in a
marine environment. Notothenioids diversified from a single common ancestor∼ 22 Mya to …

The shift from outcrossing to self-fertilization (selfing) is considered one of the most prevalent
evolutionary transitions in flowering plants. Selfing species tend to share similar …