Current and future directions in network biology

M Zitnik, MM Li, A Wells, K Glass, DM Gysi… - arXiv preprint arXiv …, 2023 - arxiv.org
Network biology, an interdisciplinary field at the intersection of computational and biological
sciences, is critical for deepening understanding of cellular functioning and disease. While …

Polyhydroxyalkanoates, the Biopolymers of Microbial Origin-A Review

A Ranganadhareddy… - Journal of Biochemical …, 2022 - jbiochemtech.com
Because petroleum-based plastics are not biodegradable, as well as the energy they
require in their production, the rising plastic substantially contributes to the depletion of the …

Shortest hyperpaths in directed hypergraphs for reaction pathway inference

S Krieger, J Kececioglu - Journal of Computational Biology, 2023 - liebertpub.com
Signaling and metabolic pathways, which consist of chains of reactions that produce target
molecules from source compounds, are cornerstones of cellular biology. Properly modeling …

Computing optimal factories in metabolic networks with negative regulation

S Krieger, J Kececioglu - Bioinformatics, 2022 - academic.oup.com
Motivation A factory in a metabolic network specifies how to produce target molecules from
source compounds through biochemical reactions, properly accounting for reaction …

Computing shortest hyperpaths for pathway inference in cellular reaction networks

S Krieger, J Kececioglu - International Conference on Research in …, 2023 - Springer
Signaling and metabolic pathways, which consist of a series of reactions producing target
molecules from source compounds, are cornerstones of cellular biology. The cellular …

Algorithmic Inference of Cellular Reaction Pathways and Protein Secondary Structure

S Krieger - 2022 - search.proquest.com
Proteins are biological molecules that carry out a multitude of cellular functions. Their
function is largely determined by the shape of the folded molecule within the cell—called …

Computing Robust Optimal Factories in Metabolic Reaction Networks

S Krieger, J Kececioglu - International Conference on Research in …, 2024 - Springer
Perhaps the most fundamental model in synthetic and systems biology for inferring
pathways in metabolic reaction networks is a metabolic factory: a system of reactions that …