Follicular dendritic cells (FDC) are mesenchymal-derived dendritic cells located in B-follicles
where they play a pivotal role in triggering and maintaining B-cell adaptive immune …

With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

ALK-positive histiocytosis is a rare subtype of histiocytic neoplasm first described in 2008 in
3 infants with multisystemic disease involving the liver and hematopoietic system. This entity …

Context.—Histiocytic sarcoma is a rare neoplasm of mature histiocytes with an aggressive
clinical course that can arise de novo or from a low-grade B-cell lymphoma. In particular …

Recent studies have demonstrated recurrent activating mutations involving the classical
MAPK and PI3K signaling pathways in a large proportion of histiocytic neoplasms, such as …

Histiocytic sarcoma is a rare malignant neoplasm that may occur de novo or in the context of
a previous hematologic malignancy or mediastinal germ cell tumor. Here, we performed …

Histiocytic disorders are a spectrum of rare diseases characterised by the accumulation of
macrophage‐, dendritic cell‐, or monocyte‐differentiated cells in various tissues and organs …

Histiocytic sarcoma and tumors with dendritic cell differentiation (HDT) are uncommon
neoplasms often with an aggressive clinical course that may occur in association with …

Disease progression in myelodysplastic syndromes (MDS), myelodysplastic-
myeloproliferative neoplasms (MDS/MPN), and myeloproliferative neoplasms (MPN) …

Originally described as a systemic self-limiting disease in infancy, the spectrum of ALK-
positive histiocytosis has recently been broadened to include localized diseases in older …