This article summarizes anatomical, neurophysiological, pharmacological, and brain
imaging studies in humans and animals that have provided insights into the neural circuitry …

Most of us live blissfully unaware of the orchestrated function that our internal organs
conduct. When this peace is interrupted, it is often by routine sensations of hunger and urge …

Henry Miller stated that “to relieve a full bladder is one of the great human joys”. Urination is
critically important in health and ailments of the lower urinary tract cause high pathological …

The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …

Functions of the lower urinary tract to store and periodically eliminate urine are regulated by
a complex neural control system in the brain, spinal cord, and peripheral autonomic ganglia …

The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal
cord, providing sensory input to the micturition centers within the central nervous system …

Background The PDE5 inhibitor tadalafil is investigation for the treatment of lower urinary
tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). Several clinical …

The proper function of the organs that make up the urinary tract (kidneys, ureters, bladder,
and urethra) depends on their ability to sense and respond to mechanical forces, including …

Purpose To determine the prevalence of, and associated risk factors for, voiding and storage
lower urinary tract symptoms (LUTS) in a population-based sample of Australian men …

Disruptions to sensory pathways in the lower urinary tract commonly occur and can give rise
to lower urinary tract symptoms (LUTS). The unmet clinical need for treatment of LUTS has …