Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics
Fluorescence imaging in the second near-infrared window (NIR-II) has become a prevalent
choice owing to its appealing advantages like deep penetration depth, low …
choice owing to its appealing advantages like deep penetration depth, low …
[HTML][HTML] The evolution of fluorescence-guided surgery
S Van Keulen, M Hom, H White, EL Rosenthal… - Molecular Imaging and …, 2023 - Springer
There has been continual development of fluorescent agents, imaging systems, and their
applications over the past several decades. With the recent FDA approvals of 5 …
applications over the past several decades. With the recent FDA approvals of 5 …
Fluorescence lifetime of injected indocyanine green as a universal marker of solid tumours in patients
R Pal, TM Lwin, M Krishnamoorthy… - Nature Biomedical …, 2023 - nature.com
The surgical resection of solid tumours can be enhanced by fluorescence-guided imaging.
However, variable tumour uptake and incomplete clearance of fluorescent dyes reduces the …
However, variable tumour uptake and incomplete clearance of fluorescent dyes reduces the …
Recent advances in chemotherapy-based organic small molecule theranostic reagents
X Rong, C Liu, X Li, H Zhu, K Wang, B Zhu - Coordination Chemistry …, 2022 - Elsevier
The growing number of cancer patients and the limitations of traditional treatments are
forcing researchers to develop more effective treatment methods. Precision medicine with …
forcing researchers to develop more effective treatment methods. Precision medicine with …
[HTML][HTML] Image-guided cancer surgery: a narrative review on imaging modalities and emerging nanotechnology strategies
B Bortot, A Mangogna, G Di Lorenzo, G Stabile… - Journal of …, 2023 - Springer
Surgical resection is the cornerstone of solid tumour treatment. Current techniques for
evaluating margin statuses, such as frozen section, imprint cytology, and intraoperative …
evaluating margin statuses, such as frozen section, imprint cytology, and intraoperative …
Comparison of fluorescence lifetime and multispectral imaging for quantitative multiplexing in biological tissue
Fluorescence lifetime (FLT) multiplexing and multispectral imaging (MSI) are both frequently
employed for in vitro and ex vivo biological studies. In vivo applications of MSI for deep …
employed for in vitro and ex vivo biological studies. In vivo applications of MSI for deep …
Light‐Responsive Nanoassemblies: Advancing Biomedical Innovation
The integrative use of light and nanoassemblies has made a profound impact in the
biomedical field for diagnosis, drug delivery, and phototherapy. Recent advances in the …
biomedical field for diagnosis, drug delivery, and phototherapy. Recent advances in the …
Miniaturized Fab'imaging probe derived from a clinical antibody: characterization and imaging in CRISPRi-attenuated mammary tumor models.
S Gupta, R Pal, EJ Schmidt, M Krishnamoorthy… - iScience, 2024 - cell.com
Clinical imaging-assisted oncosurgical navigation requires cancer-specific miniaturized
optical imaging probes. We report a near-infrared (NIR) Fab'-based epidermal growth factor …
optical imaging probes. We report a near-infrared (NIR) Fab'-based epidermal growth factor …
Infrared Fluorescence-guided Surgery for Tumor and Metastatic Lymph Node Detection in Head and Neck Cancer
HW White, AB Naveed, BR Campbell, YJ Lee… - Radiology: Imaging …, 2024 - pubs.rsna.org
In patients with head and neck cancer (HNC), surgical removal of cancerous tissue presents
the best overall survival rate. However, failure to obtain negative margins during resection …
the best overall survival rate. However, failure to obtain negative margins during resection …
[HTML][HTML] In vivo quantification of programmed death-ligand-1 expression heterogeneity in tumors using fluorescence lifetime imaging
Cancer patient selection for immunotherapy is often based on programmed death-ligand-1
(PD-L1) expression as a biomarker. PD-L1 expression is currently quantified using …
(PD-L1) expression as a biomarker. PD-L1 expression is currently quantified using …