COVID-19: breaking down a global health crisis

SI Mallah, OK Ghorab, S Al-Salmi, OS Abdellatif… - Annals of clinical …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is the second pandemic of the twenty-first
century, with over one-hundred million infections and over two million deaths to date. It is a …

Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation

SX Gu, T Tyagi, K Jain, VW Gu, SH Lee… - Nature Reviews …, 2021 - nature.com
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …

The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …

SARS-CoV-2, uncontrolled diabetes and corticosteroids—an unholy trinity in invasive fungal infections of the maxillofacial region? A retrospective, multi-centric …

A Moorthy, R Gaikwad, S Krishna, R Hegde… - Journal of maxillofacial …, 2021 - Springer
Objectives Collate and analyse data of maxillofacial/rhino-cerebro-orbital fungal infections
reported during the era of the Covid-19 pandemic, with the aim of investigating the common …

Postmortem examination of COVID‐19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs …

T Menter, JD Haslbauer, R Nienhold, S Savic… - …, 2020 - Wiley Online Library
Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2), has rapidly evolved into a sweeping pandemic. Its major …

Coagulopathy of coronavirus disease 2019

T Iba, JH Levy, M Levi, JM Connors… - Critical care …, 2020 - journals.lww.com
Objectives: Recent studies have reported a high prevalence of thrombotic events in
coronavirus disease 2019. However, the significance of thromboembolic complications has …

The unique characteristics of COVID-19 coagulopathy

T Iba, JH Levy, JM Connors, TE Warkentin, J Thachil… - Critical care, 2020 - Springer
Thrombotic complications and coagulopathy frequently occur in COVID-19. However, the
characteristics of COVID-19-associated coagulopathy (CAC) are distinct from those seen …

Thrombosis in COVID‐19

TC Hanff, AM Mohareb, J Giri, JB Cohen… - American journal of …, 2020 - Wiley Online Library
Thrombotic complications are frequent in COVID‐19 and contribute significantly to mortality
and morbidity. We review several mechanisms of hypercoagulability in sepsis that may be …

Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients

JC Holter, SE Pischke, E de Boer… - Proceedings of the …, 2020 - National Acad Sciences
Respiratory failure in the acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic is hypothesized to be driven by an overreacting innate immune response, where …

Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition

J Yu, X Yuan, H Chen, S Chaturvedi… - Blood, The Journal …, 2020 - ashpublications.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious
respiratory virus that can lead to venous/arterial thrombosis, stroke, renal failure, myocardial …