The role of high-density lipoprotein cholesterol, apolipoprotein A and paraoxonase-1 in the pathophysiology of neuroprogressive disorders
G Morris, BK Puri, CC Bortolasci, A Carvalho… - Neuroscience & …, 2021 - Elsevier
Lowered high-density lipoprotein (HDL) cholesterol has been reported in major depressive
disorder, bipolar disorder, first episode of psychosis, and schizophrenia. HDL, its major …
disorder, bipolar disorder, first episode of psychosis, and schizophrenia. HDL, its major …
[HTML][HTML] Interdependence of anti-inflammatory and antioxidant properties of squalene–implication for cardiovascular health
NI Ibrahim, I Naina Mohamed - Life, 2021 - mdpi.com
Cardiovascular diseases (CVD) have been recognized as the leading cause of mortality
worldwide, accounting for 31% of global mortality. Among the risk factors of CVD …
worldwide, accounting for 31% of global mortality. Among the risk factors of CVD …
[HTML][HTML] Modulatory effect of lifestyle-related, environmental and genetic factors on paraoxonase-1 activity: a review
D Kunachowicz, M Ściskalska, M Kepinska - International Journal of …, 2023 - mdpi.com
Paraoxonase-1 (PON1) is a calcium-dependent, HDL-bound serum hydrolase active toward
a wide variety of substrates. PON1 displays three types of activities, among which lactonase …
a wide variety of substrates. PON1 displays three types of activities, among which lactonase …
[HTML][HTML] Paraoxonases activities and polymorphisms in elderly and old-age diseases: An overview
D Levy, CO Reichert, SP Bydlowski - Antioxidants, 2019 - mdpi.com
Aging is defined as the accumulation of progressive organ dysfunction. There is much
evidence linking the involvement of oxidative stress in the pathogenesis of aging. With …
evidence linking the involvement of oxidative stress in the pathogenesis of aging. With …
Antiepileptic drugs: impacts on human serum paraoxonase‐1
Ş Beydemir, Y Demir - Journal of biochemical and molecular …, 2017 - Wiley Online Library
Serum paraoxonase (PON1) is a key enzyme related to high‐density lipoprotein (HDL)‐
cholesterol particle. It can prevent the oxidation of low‐density lipoprotein (LDL) and HDL …
cholesterol particle. It can prevent the oxidation of low‐density lipoprotein (LDL) and HDL …
Extra-virgin olive oil consumption reduces the age-related decrease in HDL and paraoxonase 1 anti-inflammatory activities
S Loued, H Berrougui, P Componova… - British Journal of …, 2013 - cambridge.org
Paraoxonase 1 (PON1) is associated with HDL and modulates the antioxidant and anti-
inflammatory role of HDL. The goals of the present study were to investigate the effect of …
inflammatory role of HDL. The goals of the present study were to investigate the effect of …
Hesperidin attenuates altered redox homeostasis in an experimental hyperlipidaemic model of rat
Diets rich in saturated fats and cholesterol contribute to the incidence of hyperlipidaemia. An
altered lipid profile is a major factor responsible for the development of CVD. Male Wistar …
altered lipid profile is a major factor responsible for the development of CVD. Male Wistar …
Onion extract (Allium cepa L.), quercetin and catechin up‐regulate paraoxonase 1 activity with concomitant protection against low‐density lipoprotein oxidation in …
N Jaiswal, SI Rizvi - Journal of the Science of Food and …, 2014 - Wiley Online Library
Abstract BACKGROUND Paraoxonase 1 (PON1) protects the oxidative modification of low‐
density lipoprotein (LDL) and is a major anti‐atherosclerotic protein component of high …
density lipoprotein (LDL) and is a major anti‐atherosclerotic protein component of high …
Hesperidin supplementation improves altered PON-1, LDL oxidation, inflammatory response and hepatic function in an experimental rat model of hyperlipidemia
In this study, we have examined the effect of hesperidin on rats fed on an experimental high-
fat diet. Male Wistar rats were given a high-fat diet orally for one month for developing an …
fat diet. Male Wistar rats were given a high-fat diet orally for one month for developing an …
[HTML][HTML] Decreases in paraoxonase-1 activities promote a pro-inflammatory effect of lipids peroxidation products in non-smoking and smoking patients with acute …
G Marek, M Ściskalska, Z Grzebieniak… - International Journal of …, 2018 - ncbi.nlm.nih.gov
Aim: The study investigated the extent to which tobacco smoke exposure causes changes in
lipids biochemistry through measurement blood concentrations of: paraoxonase-1 (PON-1) …
lipids biochemistry through measurement blood concentrations of: paraoxonase-1 (PON-1) …