Humans and other mammalian species possess an endogenous circadian clock system that
has evolved in adaptation to periodically reoccurring environmental changes and drives …

Circadian rhythms control almost all aspects of physiology and behavior, allowing temporal
synchrony of these processes between each other, as well as with the external environment …

The misfolding and subsequent abnormal accumulation and aggregation of α-Synuclein
(αSyn) as insoluble fibrils in Lewy bodies and Lewy neurites is the pathological hallmark of …

The circadian clock system works not only as a cellular time-keeper but also as a
coordinator for almost all physiological functions essential to maintaining human health …

Background Upregulation of the PD-L1 (CD274) immune checkpoint ligand on the tumor
surface facilitates tumor immune escape and limits the application of immunotherapy in …

Enhancing lighting conditions in institutions for individuals with dementia improves their
sleep, circadian rhythms and well-being. Here, we report first findings that exposure to …

We found that circadian changes in ATP level in peripheral blood (PB) activate the Nlrp3
inflammasome, which triggers diurnal release of hematopoietic stem/progenitor cells …

Antimicrobial peptides (AMPs) are important components of the innate immune system and
are involved in skin protection against environmental insults and in wound healing. Herein …

Data from human and animal studies are highly suggestive of an influence of time of day of
vaccine administration on host immune responses. In this population-based study, we aimed …

Background: Labor pain perception has been demonstrated to exhibit a circadian rhythm
with lower pain scores during the day compared with the night. This study aimed to …