Macrophages, which are functional plasticity cells, have the ability to phagocytize and digest
foreign substances and acquire pro-(M1-like) or anti-inflammatory (M2-like) phenotypes …

Non-alcoholic fatty liver disease (NAFLD) has now become the leading chronic liver disease
worldwide with lifestyle changes. This may lead to NAFLD becoming the leading cause of …

Background: Liver fibrosis affects millions of people worldwide without an effective
treatment. Although multiple cell types in the liver contribute to the fibrogenic process …

Background Receptor-interacting protein kinase 3 (RIPK3), a component of necroptosis
pathways, may have an independent role in inflammation. It has been unclear which RIPK3 …

Pulmonary hypertension (PH) is a cardiovascular disease caused by extensive vascular
remodeling in the lungs, which ultimately leads to death in consequence of right ventricle …

The gut–liver axis has been increasingly recognized as a major autoimmunity modulator.
However, the implications of intestinal barrier in the pathogenesis of autoimmune hepatitis …

Background Although diabetes mellitus has been reported to aggravate liver ischaemia and
reperfusion (IR) injury, the basic mechanism remains largely unknown. The object of the …

Necroptosis, a novel programmed cell death, plays a critical role in the development of
fibrosis, yet its role in atrial fibrillation (AF) remains elusive. Mounting evidence …

Abstract Long non‐coding RNAs (LncRNAs) and DNA methylation are important epigenetic
mark play a key role in liver fibrosis. Currently, how DNA methylation and LncRNAs control …

Previous studies have shown that lncRNA small nuclear RNA host gene 7 (lncRNA SNHG7)
played an important role in cancer progression. However, the role of lncRNA SNHG7 in …