Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …

Protecting the whole small intestine from radiation-induced intestinal injury during the
radiotherapy of abdominal or pelvic solid tumors remains an unmet clinical need. Amifostine …

Selenoprotein plays a crucial role in immune cells and inflammatory regulation. However, as
a protein drug that is easily denatured or degraded in the acidic environment of the stomach …

Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …

Polypeptide-based nanoparticles are one of the promising excipients of nanomedicines due
to their excellent biosafety and flexible modification. Among all the types of polypeptide …

Oral administration is a widespread and convenient drug delivery approach. However, oral
delivery can be affected by the complex digestive tract environment, including irregular …

The oral delivery of probiotics is commonly adopted for intestinal disease treatments in
clinical settings; however, the probiotics suffer from a strong acidic attack in the gastric area …

Lipid nanoparticle‐based drug delivery systems have a profound clinical impact on nucleic
acid‐based therapy and vaccination. Recombinant human insulin, a negatively‐charged …

The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …