The role of autophagy in bone metabolism and clinical significance
J Wang, Y Zhang, J Cao, Y Wang, N Anwar, Z Zhang… - Autophagy, 2023 - Taylor & Francis
The skeletal system is the basis of the vertebral body composition, which affords stabilization
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …
Intercellular mitochondrial transfer as a means of tissue revitalization
D Liu, Y Gao, J Liu, Y Huang, J Yin, Y Feng… - Signal transduction and …, 2021 - nature.com
As the crucial powerhouse for cell metabolism and tissue survival, the mitochondrion
frequently undergoes morphological or positional changes when responding to various …
frequently undergoes morphological or positional changes when responding to various …
Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases
Z Liu, Y Sun, Z Qi, L Cao, S Ding - Cell & bioscience, 2022 - Springer
Mitochondria play a pivotal role in energy generation and cellular physiological processes.
These organelles are highly dynamic, constantly changing their morphology, cellular …
These organelles are highly dynamic, constantly changing their morphology, cellular …
[HTML][HTML] Biological functions of mesenchymal stem cells and clinical implications
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
Blood contains circulating cell free respiratory competent mitochondria
ZAA Dache, A Otandault, R Tanos, B Pastor, R Meddeb… - Faseb Journal, 2020 - hal.science
Mitochondria are considered as the power-generating units of the cell due to their key role in
energy metabolism and cell signaling. However, mitochondrial components could be found …
energy metabolism and cell signaling. However, mitochondrial components could be found …
Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming
J Levoux, A Prola, P Lafuste, M Gervais, N Chevallier… - Cell metabolism, 2021 - cell.com
Platelets are known to enhance the wound-healing activity of mesenchymal stem cells
(MSCs). However, the mechanism by which platelets improve the therapeutic potential of …
(MSCs). However, the mechanism by which platelets improve the therapeutic potential of …
Manufacturing of primed mesenchymal stromal cells for therapy
JQ Yin, J Zhu, JA Ankrum - Nature biomedical engineering, 2019 - nature.com
Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …
manufactured and developed as unique cell products by many different manufacturers and …
Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs
K Todkar, L Chikhi, V Desjardins, F El-Mortada… - Nature …, 2021 - nature.com
Most cells constitutively secrete mitochondrial DNA and proteins in extracellular vesicles
(EVs). While EVs are small vesicles that transfer material between cells, Mitochondria …
(EVs). While EVs are small vesicles that transfer material between cells, Mitochondria …
Regenerative abilities of mesenchymal stem cells through mitochondrial transfer
The past decade has witnessed an upsurge in studies demonstrating mitochondrial transfer
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …
Mitochondria as a therapeutic target for ischemic stroke
Z He, N Ning, Q Zhou, SE Khoshnam… - Free Radical Biology and …, 2020 - Elsevier
Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …