Medulloblastoma (MB) is a major pediatric malignant brain tumor that arises in the
cerebellum. MB tumors exhibit highly heterogeneous driven by diverse genetic alterations …

Simple Summary Patients with medulloblastoma receive treatment according to a risk
stratification, which is a combination of clinical and biological factors. To date there have …

The preclinical and clinical development of novel immunotherapies for the treatment of
central nervous system (CNS) tumors is advancing at a rapid pace. High-grade gliomas …

Medulloblastoma is the most common malignant brain tumor in children. Over the last few
decades, significant progress has been made in revealing the key molecular underpinnings …

Objective Exosomes, membranous nanovesicles, naturally bringing proteins, mRNAs, and
microRNAs (miRNAs), play crucial roles in tumor pathogenesis. This study was to …

Medulloblastoma (MB) is the most common malignant brain tumor in children, making up~
20% of all primary pediatric brain tumors. Current therapies consist of maximal surgical …

Medulloblastoma (MB) is a highly malignant childhood tumor of the cerebellum.
Transcriptional and epigenetic signatures have classified MB into four molecular subgroups …

Introduction Medulloblastoma is the most common and lethal pediatric malignant brain
tumor. It comprises four main molecular subgroups: WNT-activated, SHH-activated, Group 3 …

Medulloblastoma is the most common malignant brain tumor of childhood accounting for
about 60% of all pediatric embryonal tumors. Despite improvements in the overall survival …

Simple Summary Tumours of the central nervous system (CNS) are the most common solid
tumours in children. The difficulties in treating this complicated variety of tumours are that …