During aging and after traumatic injuries, cartilage and bone cells are exposed to various
pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated …

Alzheimer's disease (AD) is a neurodegenerative disease mainly characterized by
progressive cognitive dysfunction and memory impairment. Recent studies have shown that …

Osteoarthritis (OA) is the most common degenerative joint disease characterized by
enzymatic degradation of the cartilage extracellular matrix (ECM) causing joint pain and …

Chondrocytes are the main cell type in articular cartilage. They are embedded in an
avascular, abundant, and specialized extracellular matrix (ECM). Chondrocytes are …

Oxidative stress is an important, but elusive, therapeutic target for osteoarthritis (OA).
Antioxidant strategies that target oxidative stress through the elimination of reactive oxygen …

Oxidative stress has a significant impact on the occurrence of many chronic diseases.
Antioxidants have ability to prevent, postpone or treat effects of free radicals. Resveratrol is a …

Osteoarthritis (OA), a prevalent degenerative joint disease, affects a substantial global
population. Despite the elusive etiology of OA, recent investigations have implicated …

Introduction Estrogens play a considerable role in maintaining bone and articular cartilage
homeostasis. Menopause provokes joint disorders due to metabolic syndrome and altered …

Osteoarthritis (OA) is a degenerative disease of the joints that affects greatly the elderly
population and the health care systems and is on the increase due to aging and obesity …

Osteoporosis (OP) is one of the most common metabolic skeletal disorders and is commonly
seen in the elderly population and postmenopausal women. It is mainly associated with …