Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance
Obesity is an important contributing factor to the pathophysiology of atrial fibrillation (AF) and
its complications by causing systemic changes, such as altered haemodynamic, increased …
its complications by causing systemic changes, such as altered haemodynamic, increased …
Role of RIPK3‑CaMKII‑mPTP signaling pathway‑mediated necroptosis in cardiovascular diseases
S Chen, S Guan, Z Yan, F Ouyang… - International …, 2023 - spandidos-publications.com
Necroptosis, which is distinct from apoptosis and necrosis, serves a crucial role in ontogeny
and the maintenance of homeostasis. In the last decade, it has been demonstrated that the …
and the maintenance of homeostasis. In the last decade, it has been demonstrated that the …
Hybrid nanogenerator based closed-loop self-powered low-level vagus nerve stimulation system for atrial fibrillation treatment
Atrial fibrillation is an “invisible killer” of human health. It often induces high-risk diseases,
such as myocardial infarction, stroke, and heart failure. Fortunately, atrial fibrillation can be …
such as myocardial infarction, stroke, and heart failure. Fortunately, atrial fibrillation can be …
[HTML][HTML] Potential mechanism underlying exercise upregulated circulating blood exosome miR-215-5p to prevent necroptosis of neuronal cells and a model for early …
Exercise is crucial for preventing Alzheimer's disease (AD), although the exact underlying
mechanism remains unclear. The construction of an accurate AD risk prediction model is …
mechanism remains unclear. The construction of an accurate AD risk prediction model is …
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and …
Y Zhang, Y Fu, T Jiang, B Liu, H Sun, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in clinical setting. Its
pathogenesis was associated with metabolic disorder, especially defective fatty acids …
pathogenesis was associated with metabolic disorder, especially defective fatty acids …
Effects of inflammatory cell death caused by catheter ablation on atrial fibrillation
D Liu, Y Li, Q Zhao - Journal of Inflammation Research, 2023 - Taylor & Francis
Atrial fibrillation (AF) poses a serious healthcare burden on society due to its high morbidity
and the resulting serious complications such as thrombosis and heart failure. The principle …
and the resulting serious complications such as thrombosis and heart failure. The principle …
Restoring the autonomic balance in an atrial fibrillation rat model by electroacupuncture at the neiguan point
Y Su, J Huang, S Sun, T He, T Wang, M Fan… - … : Technology at the …, 2022 - Elsevier
Objectives Autonomic nervous activity imbalance plays an important role in atrial fibrillation
(AF). AF can be treated by acupuncture at the Neiguan point (PC6), but the mechanism …
(AF). AF can be treated by acupuncture at the Neiguan point (PC6), but the mechanism …
Linagliptin ameliorated cardiac fibrosis and restored cardiomyocyte structure in diabetic mice associated with the suppression of necroptosis
J Adhikari, T Hirai, E Kawakita, K Iwai… - Journal of Diabetes …, 2023 - Wiley Online Library
ABSTRACT Aims/Introduction Linagliptin is a selective dipeptidyl peptidase (DPP)‐4
inhibitor capable of successfully regulating blood glucose levels. The cardiovascular …
inhibitor capable of successfully regulating blood glucose levels. The cardiovascular …
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload
X Qin, Y Fu, J Fan, B Liu, P Liu, Y Zhang… - Journal of Pineal …, 2023 - Wiley Online Library
Melatonin has been proven to have antiarrhythmic potential; however, several studies have
recently challenged this view. Herein, using a mouse model of obesity‐induced atrial …
recently challenged this view. Herein, using a mouse model of obesity‐induced atrial …
Targeting necroptosis in fibrosis
EHM Hassanein, IM Ibrahim… - Molecular Biology …, 2023 - Springer
Necroptosis, a type of programmed cell death that resembles necrosis, is now known to
depend on a different molecular mechanism from apoptosis, according to several recent …
depend on a different molecular mechanism from apoptosis, according to several recent …