[HTML][HTML] Thalamic nuclei changes in early and late onset Alzheimer's disease

G Forno, M Saranathan, J Contador, N Guillen… - Current Research in …, 2023 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia worldwide. Increasing
evidence points to the thalamus as an important hub in the clinical symptomatology of the …

[HTML][HTML] The cognitive dysfunction of claustrum on Alzheimer's disease: A mini-review

CY Chen, GY Yang, HX Tu, XC Weng, C Hu… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases
characterized by cognitive deficits and dementia. AD entails predominant pathological …

[HTML][HTML] Atypical clinical variants of Alzheimer's disease: are they really atypical?

JL Whitwell - Frontiers in Neuroscience, 2024 - frontiersin.org
Alzheimer's disease (AD) is a neuropathological disorder defined by the deposition of the
proteins, tau and β-amyloid. Alzheimer's disease is commonly thought of as a disease of the …

[HTML][HTML] Cortical thickness modeling and variability in Alzheimer's disease and frontotemporal dementia

A Pérez-Millan, S Borrego-Écija, N Falgàs… - Journal of …, 2024 - Springer
Background and objective Alzheimer's disease (AD) and frontotemporal dementia (FTD)
show different patterns of cortical thickness (CTh) loss compared with healthy controls (HC) …

[HTML][HTML] Reduced Salivary Lactoferrin Levels in Early-Onset Alzheimer's Disease

D Antequera, L Carrero, M Gonzalez-Sanchez… - Aging and …, 2024 - ncbi.nlm.nih.gov
Decreased salivary lactoferrin levels were reported in patients suffering from mild cognitive
impairment (MCI) and AD compared with age-matched healthy subjects [1], indicating a …

Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early‐onset Alzheimer's disease

S Nemes, PE Logan, MK Manchella… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION We used sex and apolipoprotein E ε4 (APOE ε4) carrier status as
predictors of pathologic burden in early‐onset Alzheimer's disease (EOAD). METHODS We …

The Effects of PICALM rs3851179 and Age on Brain Atrophy and Cognition Along the Alzheimer's Disease Continuum

Z Wu, J Chen, Y Liu, Y Yang, M Feng, H Dai… - Molecular …, 2024 - Springer
Rs3851179, a variant of PICALM gene, and age are the risk factors of Alzheimer's disease
(AD). AD is divided into early-onset AD (EOAD,< 65 years) and late-onset AD (LOAD,≥ 65 …

Prospective trajectories of depression predict mortality in cancer patients

DE Sanghvi, MS Chen, GA Bonanno - Journal of Behavioral Medicine, 2024 - Springer
An ever-growing body of empirical evidence has demonstrated the relationship between
depression and cancer. The objective of this study was to examine whether depression …

[HTML][HTML] Cerebrospinal Fluid Biomarkers and Cognitive Trajectories in Patients with Alzheimer's Disease and a History of Traumatic Brain Injury

S van Amerongen, S Das, S Kamps, J Goossens… - Neurobiology of …, 2024 - Elsevier
Traumatic brain injury (TBI) and Alzheimer's disease (AD) have overlapping mechanisms
but it remains unknown if pathophysiological characteristics and cognitive trajectories in AD …

Neuropsychological Profiles, Etiologies, and Medical Comorbidities in Early-Onset Dementia and Cognitive Impairment: A Memory Outpatient Clinic Cohort Study

AL Heikkinen, TI Paajanen, T Hänninen… - Journal of …, 2024 - content.iospress.com
Background: Although early-onset dementia (EOD) is associated with diagnostic challenges
that differ from those of related to late-onset dementia, only limited studies have addressed …