[HTML][HTML] Spirometric indices of early airflow impairment in individuals at risk of developing COPD: spirometry beyond FEV1/FVC

D Hoesterey, N Das, W Janssens, RG Buhr… - Respiratory …, 2019 - Elsevier
Spirometry is the current gold standard for diagnosing and monitoring the progression of
Chronic Obstructive Pulmonary Disease (COPD). However, many current and former …

[HTML][HTML] Fractal analysis of lung structure in chronic obstructive pulmonary disease

N Tanabe, S Sato, B Suki, T Hirai - Frontiers in physiology, 2020 - frontiersin.org
Chest CT is often used for localizing and quantitating pathologies associated with chronic
obstructive pulmonary disease (COPD). While simple measurements of areas and volumes …

[HTML][HTML] The effect of flow on swimming bacteria controls the initial colonization of curved surfaces

E Secchi, A Vitale, GL Miño, V Kantsler, L Eberl… - Nature …, 2020 - nature.com
The colonization of surfaces by bacteria is a widespread phenomenon with consequences
on environmental processes and human health. While much is known about the molecular …

Identification of COPD from multi-view snapshots of 3D lung airway tree via deep CNN

R Du, S Qi, J Feng, S Xia, Y Kang, W Qian… - IEEE Access, 2020 - ieeexplore.ieee.org
Chronic obstructive pulmonary disease (COPD) is associated with morphologic
abnormalities of airways with various patterns and severities. However, the way of effectively …

[HTML][HTML] An entropy-based measure of complexity: An application in lung-damage

P Ortiz-Vilchis, A Ramirez-Arellano - Entropy, 2022 - mdpi.com
The computed tomography (CT) chest is a tool for diagnostic tests and the early evaluation
of lung infections, pulmonary interstitial damage, and complications caused by common …

Steady and oscillatory flow in the human bronchial tree

S Jalal, T Van de Moortele, O Amili, F Coletti - Physical Review Fluids, 2020 - APS
In this study, we investigate the steady inhalation, steady exhalation, and oscillatory flow in a
realistic airway geometry for physiologically relevant regimes ranging from quiet breathing to …

Topological analysis of particle transport in lung airways: Predicting particle source and destination

A Farghadan, F Coletti, A Arzani - Computers in biology and medicine, 2019 - Elsevier
Particle transport in lung airways can induce respiratory disease and play a vital role in
aerosol drug delivery. Herein, we present dynamical systems features that influence airflow …

Initiating drug therapy in early stage chronic obstructive pulmonary disease: does it impact the course and outcome?

RM Burkes, MB Drummond - Current opinion in pulmonary …, 2019 - journals.lww.com
Early COPD is an important manifestation of COPD, with a newly proposed definition and
associated risk factors identified. Inferring from studies on mild COPD cohorts, LAMAs and …

Aerodynamic Simulation of Small Airway Resistance: A New Imaging Biomarker for Chronic Obstructive Pulmonary Disease

D Zhang, Y Guan, X Zhou, M Zhang, Y Pu… - … Journal of Chronic …, 2024 - Taylor & Francis
Purpose To develop a novel method for calculating small airway resistance using
computational fluid dynamics (CFD) based on CT data and evaluate its value to identify …

[HTML][HTML] Plasma cathelicidin and longitudinal lung function in current and former smokers

RM Burkes, J Astemborski, AA Lambert, TT Brown… - PloS one, 2019 - journals.plos.org
Introduction Cathelicidin (also known as LL-37 in humans) is an antimicrobial peptide
secreted by epithelial and immune cells and regulated by vitamin D. The immunological …