Neutrophils are immune cells with unusual biological features that furnish potent
antimicrobial properties. These cells phagocytose and subsequently kill prokaryotic and …

Chemokines are recognized as the most critical mediators for selective neutrophil
recruitment during inflammatory conditions. Furthermore, they are considered fundamental …

Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …

The concept that chemokines, cytokines and pro-inflammatory mediators act in a co-
ordinated fashion to drive the initiation of the inflammatory reaction is well understood. The …

Comprising the majority of leukocytes in humans, neutrophils are the first immune cells to
respond to inflammatory or infectious etiologies and are crucial participants in the proper …

Neutrophils are the most abundant white blood cells in circulation, and patients with
congenital neutrophil deficiencies suffer from severe infections that are often fatal …

Platelets are most often recognized for their crucial role in the control of acute hemorrhage.
However, current research has greatly expanded the appreciation of platelets beyond their …

The immune system has evolved to protect the host from a universe of pathogenic microbes
that are themselves constantly evolving. The immune system also helps the host eliminate …

Nonresolving inflammation is a major driver of disease. Perpetuation of inflammation is an
inherent risk because inflammation can damage tissue and necrosis can provoke …

Polymorphonuclear leukocytes or neutrophils play a critical role in the maintenance of
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …