Significance: Chronic wounds impact the quality of life (QoL) of nearly 2.5% of the total
population in the United States and the management of wounds has a significant economic …

The presence of biofilms in chronic non-healing wounds, has been identified through in vitro
model and in vivo animal data. However, human chronic wound studies are under …

Significance: A 2018 retrospective analysis of Medicare beneficiaries identified that∼ 8.2
million people had wounds with or without infections. Medicare cost estimates for acute and …

Biofilm infection has a high prevalence in chronic wounds and can delay wound healing.
Current treatment using debridement and antibiotic administration imposes a significant …

The treatment of chronic wounds still challenges modern medicine because of these
wounds' heterogenic pathophysiology. Processes such as inflammation, ischemia and …

Biofilms play a major role in delaying chronic wounds from healing. A wound infiltrated with
biofilm, or “critically colonised” wound, may become clinically infected if the number of …

The Centers for Disease Control and Prevention estimate for human infectious diseases
caused by bacteria with a biofilm phenotype is 65 percent and the National Institutes of …

Objective: The objective of this work was to causatively link biofilm properties of bacterial
infection to specific pathogenic mechanisms in wound healing. Background: Staphylococcus …

Biofilms are increasingly recognised as a critical global issue in a multitude of industries
impacting health, food and water security, marine sector, and industrial processes resulting …

Pseudomonas aeruginosa is an opportunistic, nosocomial bacterial pathogen that forms
persistent infections due to the formation of protective communities, known as biofilms. Once …