Current status of DNA sequencing by single molecule detection

JH Werner, H Cai, PM Goodwin… - … Sensing Technology IV, 1999 - spiedigitallibrary.org
Our current experiments further the development of a laser-based technique capable of
sequencing an individual strand of DNA. We report the detection and identification of …

Enzymatic nucleic acid synthesis: compositions and methods for inhibiting pyrophosphorolysis

SH Hardin, X Gao, J Briggs, R Willson… - US Patent 8,648,179, 2014 - Google Patents
Nucleotide triphosphate probes containing a molecular and/or atomic tag on aa γ and/or β
phosphate group and/or a base moiety having a detectable property are disclosed, and kits …

Nucleic acid sequencing by Raman monitoring of uptake of precursors during molecular replication

A Berlin, SJ Kirch, G Neubauer, V Rao… - US Patent …, 2008 - Google Patents
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Hybridization of polynucleotides conjugated with chromo-phores and fluorophores to generate donor-to-donor energy transfer system

MJ Heller - US Patent 6,416,953, 2002 - Google Patents
(*) Notice: Subject to any disclaimer, the term of this Haddon et al., Proc. Natl. Acad. Sci.
USA, 92: 1874-1878 patent is extended or adjusted under 35 (1985). USC 154 (b) by 0 …

Method for sequencing nucleic acid molecules

J Korlach, WW Webb, M Levene, S Turner… - US Patent App. 12 …, 2011 - Google Patents
0004. The goal to elucidate the entire human genome has created an interest in
technologies for rapid DNA sequencing, both for Small and large scale applications …

Enzymatic Nucleic Acid Synthesis: Compositions and Methods for Inhibiting Pyrophosphorolysis

SH Hardin, X Gao, J Briggs, R Willson… - US Patent App. 12 …, 2011 - Google Patents
Nucleotide triphosphate probes containing a molecular and/or atomic tag on aay and/or [3
phosphate group and/or a base moiety having a detectable property are disclosed, and kits …

Enzymatic nucleic acid synthesis: methods for direct detection of tagged monomers

SH Hardin, X Gao, J Briggs, R Willson… - US Patent App. 12 …, 2010 - Google Patents
Nucleotide triphosphate probes containing a molecular and/or atomic tag on a γ and/or β
phosphate group and/or a base moiety having a detectable property are disclosed, and kits …

Multibase delivery for long reads in sequencing by synthesis protocols

M Ronaghi, HA Eltoukhy - US Patent 9,005,929, 2015 - Google Patents
Related US Application Data (63) Continuation of application No. 13/905,003, filed on May
29, 2013, now Pat. No. 8,709,729, which is a continuation of application No. 13/545,682 …

Single molecule sequencing method

Z Foldes-Papp, J Holm - US Patent App. 10/311,673, 2005 - Google Patents
US20050153284A1 - Single molecule sequencing method - Google Patents
US20050153284A1 - Single molecule sequencing method - Google Patents Single …

Single molecule detection with surface-enhanced raman scattering and applications in DNA or RNA sequencing

K Kneipp, H Kneipp, I Itzkan, R Dasari… - US Patent App. 10 …, 2005 - Google Patents
Surface-enhanced spectroscopy, such as surface-enhanced Raman spectroscopy employs
aggregates that are of a size that allows easy handling. The aggregates are generally at …