Nucleic acid sequencing by Raman monitoring of uptake of nucleotides during molecular replication
The methods and apparatus disclosed herein are useful for detecting nucleotides,
nucleosides, and bases and for nucleic acid Sequence determination. The methods involve …
nucleosides, and bases and for nucleic acid Sequence determination. The methods involve …
Method for sequencing nucleic acid molecules
J Korlach, WW Webb, M Levene, S Turner… - US Patent App. 12 …, 2008 - Google Patents
The present invention is directed to a method of sequencing a target nucleic acid molecule
having a plurality of bases. In its principle, the temporal order of base additions during the …
having a plurality of bases. In its principle, the temporal order of base additions during the …
Nanoprobes for detection or modification of molecules
IG Lyakhov, TD Schneider, D Needle - US Patent 8,703,734, 2014 - Google Patents
2013-01-23 Assigned to THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE
SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES reassignment THE …
SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES reassignment THE …
High density labeling of DNA with modified or" chromophore" carrying nucleotides and DNA polymerases used
K Muehlegger, B Angerer, F Seela… - US Patent App. 10 …, 2004 - Google Patents
Subjects of the inventions are methods for enzymatic DNA labeling. Nucleotides modified to
carry functional or detect able groups are incorporated into newly Synthesized DNA by DNA …
carry functional or detect able groups are incorporated into newly Synthesized DNA by DNA …
System and method for nucleic acid sequencing by polymerase synthesis
JGK Williams - US Patent App. 11/757,289, 2008 - Google Patents
This invention relates to improved methods for sequencing and genotyping nucleic acid in a
single molecule configura tion. The method involves single molecule detection of fluo …
single molecule configura tion. The method involves single molecule detection of fluo …
Method for DNA sequencing and gene identification
Z Yang, T Qiao - US Patent App. 10/059,988, 2003 - Google Patents
A method for single molecule identification of a target DNA molecule in a random coil state
having the following steps: a) attaching an optically distinguishable material to a DNA …
having the following steps: a) attaching an optically distinguishable material to a DNA …
Stabilizing a polyelectrolyte multilayer
D Lapen - US Patent App. 11/007,831, 2006 - Google Patents
0002 Completion of the human genome has paved the way for important insights into
biologic structure and func tion. Knowledge of the human genome has given rise to inquiry …
biologic structure and func tion. Knowledge of the human genome has given rise to inquiry …
Nucleotide analogs
P Buzby - US Patent App. 11/286,516, 2007 - Google Patents
BACKGROUND There have been many proposals to develop new sequencing technologies
based on single-molecule measurements. For example, sequencing strategies have been …
based on single-molecule measurements. For example, sequencing strategies have been …
Nanopore-based nucleic acid analysis with mixed FRET detection
M Huber, BE Clancy, P Hardenbol - US Patent 9,862,997, 2018 - Google Patents
Various methods, systems and devices for optical detection and analysis of polymers, such
as polynucleotides, using nanopores, eg, for determining sequences of nucleic acids, are …
as polynucleotides, using nanopores, eg, for determining sequences of nucleic acids, are …
Nucleotides
J Korlach, W Webb, M Levene, S Turner… - US Patent App. 11 …, 2007 - Google Patents
The present invention is directed to a method of sequencing a target nucleic acid molecule
having a plurality of bases. In its principle, the temporal order of base additions during the …
having a plurality of bases. In its principle, the temporal order of base additions during the …