Nucleic acid analysis using terminal-phosphate-labeled nucleotides
J Korlach, WW Webb, M Levene, S Turner… - US Patent …, 2008 - Google Patents
The present invention is directed to a method of sequencing a target nucleic acid molecule
having a plurality of bases. In its principle, the temporal order of base additions during the …
having a plurality of bases. In its principle, the temporal order of base additions during the …
Real-time sequence determination
(57) ABSTRACT A sequencing methodology is disclosed that allows a single DNA or RNA
molecule or portion thereof to be sequenced directly and in Substantially real time. The …
molecule or portion thereof to be sequenced directly and in Substantially real time. The …
System and methods for nucleic acid sequencing of single molecules by polymerase synthesis
JGK Williams - US Patent 8,192,961, 2012 - Google Patents
This invention relates to improved methods for sequencing and genotyping nucleic acid in a
single molecule configura tion. The method involves single molecule detection of fluo …
single molecule configura tion. The method involves single molecule detection of fluo …
Methods and apparatuses for analyzing polynucleotide sequences
S Quake, EP Kartalov - US Patent 7,501,245, 2009 - Google Patents
US7501245B2 - Methods and apparatuses for analyzing polynucleotide sequences - Google
Patents US7501245B2 - Methods and apparatuses for analyzing polynucleotide sequences …
Patents US7501245B2 - Methods and apparatuses for analyzing polynucleotide sequences …
Short cycle methods for sequencing polynucleotides
S Lapidus, PR Buzby, T Harris - US Patent 7,897,345, 2011 - Google Patents
US7897345B2 - Short cycle methods for sequencing polynucleotides - Google Patents
US7897345B2 - Short cycle methods for sequencing polynucleotides - Google Patents Short …
US7897345B2 - Short cycle methods for sequencing polynucleotides - Google Patents Short …
Apparatus and method for analysis of molecules
S Turner, J Korlach - US Patent 7,302,146, 2007 - Google Patents
The present invention relates to optical confinements, meth ods of preparing and methods of
using them for analyzing molecules and/or monitoring chemical reactions. The appa ratus …
using them for analyzing molecules and/or monitoring chemical reactions. The appa ratus …
High speed parallel molecular nucleic acid sequencing
TD Schneider, D Rubens - US Patent 6,982,146, 2006 - Google Patents
(57) ABSTRACT A method and device is disclosed for high Speed, automated Sequencing
of nucleic acid molecules. A nucleic acid mol ecule to be sequenced is exposed to a …
of nucleic acid molecules. A nucleic acid mol ecule to be sequenced is exposed to a …
Computer-based methods and systems for sequencing of individual nucleic acid molecules
DC Schwartz, B Mishra - US Patent 6,221,592, 2001 - Google Patents
The present invention relates to methods and Systems for determining the nucleotide
Sequence of individual nucleic acid molecules using optical techniques, referred to herein …
Sequence of individual nucleic acid molecules using optical techniques, referred to herein …
Use of single-stranded nucleic acid binding proteins in sequencing
P Buzby - US Patent App. 10/900,711, 2006 - Google Patents
US20060024678A1 - Use of single-stranded nucleic acid binding proteins in sequencing -
Google Patents US20060024678A1 - Use of single-stranded nucleic acid binding proteins in …
Google Patents US20060024678A1 - Use of single-stranded nucleic acid binding proteins in …
System and apparatus for nucleic acid sequencing of single molecules by polymerase synthesis
JGK Williams - US Patent 6,762,048, 2004 - Google Patents
This invention provides for a method of genotyping or Sequencing a target nucleic acid INA
comprising the Steps of i. immobilizing a nucleic acid polymerase or the target nucleic acid …
comprising the Steps of i. immobilizing a nucleic acid polymerase or the target nucleic acid …