System and methods for nucleic acid sequencing of single molecules by polymerase synthesis
JGK Williams - US Patent 9,845,501, 2017 - Google Patents
US9845501B2 - System and methods for nucleic acid sequencing of single molecules by
polymerase synthesis - Google Patents US9845501B2 - System and methods for nucleic acid …
polymerase synthesis - Google Patents US9845501B2 - System and methods for nucleic acid …
Modified nucleotides, methods for making and using same
H Wang, X Gao, P Yu, M Reddy, S Hardin… - US Patent App. 11 …, 2008 - Google Patents
0002) 1. Field of the Invention 0003. The present invention relates to modified nucle otides
and methods for making and using same. 0004 More particularly, the present invention …
and methods for making and using same. 0004 More particularly, the present invention …
Method for sequencing nucleic acids by observing the uptake of nucleotides modified with bulky groups
N Sundararajan, A Berlin, M Yamakawa… - US Patent App. 11 …, 2007 - Google Patents
The present methods and apparatus concern nucleic acid sequencing by incorporation of
nucleotides into nucleic acid strands. The incorporation of nucleotides is detected by …
nucleotides into nucleic acid strands. The incorporation of nucleotides is detected by …
Compositions and methods for sequence determination
ABSTRACT A sequencing methodology is disclosed that allows a single DNA or RNA
molecule or portion thereof to be sequenced directly and in substantially real time. The …
molecule or portion thereof to be sequenced directly and in substantially real time. The …
Compositions for sequence determination using tagged polymerizing agents and tagged monomers
ABSTRACT A sequencing methodology is disclosed that allows a single DNA or RNA
molecule or portion thereof to be sequenced directly and in substantially real time. The …
molecule or portion thereof to be sequenced directly and in substantially real time. The …
Methods for nucleic acid sequence determination
P Buzby, R Ickes, J DiMeo - US Patent App. 10/831,214, 2005 - Google Patents
Methods of the invention comprise methods for nucleic acid sequence determination.
Generally, the invention relates to sequencing a target nucleic acid by exposing the target …
Generally, the invention relates to sequencing a target nucleic acid by exposing the target …
Methods for analyzing nucleic acid sequences
J Korlach, WW Webb, M Levene, S Turner… - US Patent …, 2011 - Google Patents
The present invention is directed to a method of sequencing a target nucleic acid. The
method provides a complex comprising a polymerase enzyme, a target nucleic acid …
method provides a complex comprising a polymerase enzyme, a target nucleic acid …
Sequence determination by direct detection
ABSTRACT A sequencing methodology is disclosed that allows a single DNA or RNA
molecule or portion thereof to be sequenced directly and in substantially real time. The …
molecule or portion thereof to be sequenced directly and in substantially real time. The …
Fabrication of optical confinements
S Turner, J Korlach - US Patent App. 11/229,376, 2006 - Google Patents
The present invention relates to optical confinements, methods of preparing and methods of
using them for analyzing molecules and/or monitoring chemical reactions. The apparatus …
using them for analyzing molecules and/or monitoring chemical reactions. The apparatus …