[PDF][PDF] Adipose-tissue plasticity in health and disease

A Sakers, MK De Siqueira, P Seale, CJ Villanueva - Cell, 2022 - cell.com
Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

Adipogenesis and metabolic health

AL Ghaben, PE Scherer - Nature reviews Molecular cell biology, 2019 - nature.com
Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

Adipokines in health and disease

M Fasshauer, M Blüher - Trends in pharmacological sciences, 2015 - cell.com
Obesity increases the risk for metabolic, cardiovascular, chronic inflammatory, and several
malignant diseases and, therefore, may contribute to shortened lifespan. Adipokines are …

[HTML][HTML] Adipose tissue macrophages: going off track during obesity

L Boutens, R Stienstra - Diabetologia, 2016 - Springer
Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …

Adipocyte dysfunction, inflammation and metabolic syndrome

N Klöting, M Blüher - Reviews in Endocrine and Metabolic Disorders, 2014 - Springer
Obesity is frequently associated with chronic inflammation, metabolic and vascular
alterations which predispose to the development of the Metabolic Syndrome (MetS) …

Adipose tissue inflammation: a cause or consequence of obesity-related insulin resistance?

M Blüher - Clinical science, 2016 - portlandpress.com
The worldwide obesity epidemic has become a major health concern, because it contributes
to higher mortality due to an increased risk for noncommunicable diseases including …

[PDF][PDF] Mechanisms and metabolic implications of regional differences among fat depots

T Tchkonia, T Thomou, YI Zhu, I Karagiannides… - Cell metabolism, 2013 - cell.com
Fat distribution is closely linked to metabolic disease risk. Distribution varies with sex,
genetic background, disease state, certain drugs and hormones, development, and aging …

Fat cell size: measurement methods, pathophysiological origins, and relationships with metabolic dysregulations

RZ Ye, G Richard, N Gévry, A Tchernof… - Endocrine …, 2022 - academic.oup.com
The obesity pandemic increasingly causes morbidity and mortality from type 2 diabetes,
cardiovascular diseases and many other chronic diseases. Fat cell size (FCS) predicts …

Adipose cell size: importance in health and disease

KG Stenkula… - American Journal of …, 2018 - journals.physiology.org
Adipose tissue is necessary to harbor energy. To handle excess energy, adipose tissue
expands by increasing adipocyte size (hypertrophy) and number (hyperplasia). Here, we …

Aerobic exercise in the management of metabolic dysfunction associated fatty liver disease

MV Machado - Diabetes, Metabolic Syndrome and Obesity, 2021 - Taylor & Francis
Sedentarism is the pandemic of modern times. It is associated with several medical
conditions including obesity, type 2 diabetes mellitus, cardiovascular diseases and also liver …