Broad-spectrum β-lactamase genes (coding for extended-spectrum β-lactamases and AmpC
β-lactamases) have been frequently demonstrated in the microbiota of food-producing …

Extended spectrum β-lactamases (ESBLs) are a group of enzymes that can hydrolyze a
variety of β-lactams including fourth generation cephalosporins and compromise the efficacy …

Introduction: Extended-spectrum beta-lactamases (ESBLs) are the major cause of resistance
to beta-lactam antibiotics such as penicillins, cephalosporins, and monobactams. They are …

Background Antimicrobial resistance (AMR) is widely acknowledged as a global health
problem, yet in many parts of the world its magnitude is not well elucidated. A baseline …

Background Bacterial resistance to antibiotics is becoming a serious problem worldwide.
The discovery of new and effective antimicrobials and/or resistance modulators is necessary …

Background Multi-drug resistance of Gram-negative bacteria constitutes a major obstacle in
the antibacterial fight worldwide. The discovery of new and effective antimicrobials and/or …

Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and
carbapenemase-producing Enterobacteriaceae (CPE) are widespread. Here we used the …

Background Although β-lactam antibiotics are heavily used in many developing countries,
the diversity of β-lactamase genes (bla) is poorly understood. We screened for major β …

Background Physicians depend on reliable information on the local epidemiology of
infection and antibiotic resistance rates to guide empiric treatment in critically ill patients. As …

Background There is no information regarding the resistance mechanisms of extended-
spectrum ß-lactamase (ESBL)-producing Enterobacteriaceae in community setting in …