The prostanoid EP4 receptor and its signaling pathway
U Yokoyama, K Iwatsubo, M Umemura, T Fujita… - Pharmacological …, 2013 - ASPET
The EP4 prostanoid receptor is one of four receptor subtypes for prostaglandin E2. It
belongs to the family of G protein–coupled receptors. It was originally identified, similar to …
belongs to the family of G protein–coupled receptors. It was originally identified, similar to …
The role of prostaglandins E1 and E2, dinoprostone, and misoprostol in cervical ripening and the induction of labor: a mechanistic approach
R Bakker, S Pierce, D Myers - Archives of gynecology and obstetrics, 2017 - Springer
Purpose Prostaglandins play a critical role in cervical ripening by increasing inflammatory
mediators in the cervix and inducing cervical remodeling. Prostaglandin E1 (PGE1) and …
mediators in the cervix and inducing cervical remodeling. Prostaglandin E1 (PGE1) and …
Glucose-dependent insulinotropic polypeptide: blood glucose stabilizing effects in patients with type 2 diabetes
MB Christensen, S Calanna, JJ Holst… - The Journal of …, 2014 - academic.oup.com
Context: Patients with type 2 diabetes mellitus (T2DM) have clinically relevant disturbances
in the effects of the hormone glucose-dependent insulinotropic polypeptide (GIP). Objective …
in the effects of the hormone glucose-dependent insulinotropic polypeptide (GIP). Objective …
The regulation of uterine function during parturition: an update and recent advances
Successful pregnancy necessitates that the uterus is maintained in a relaxed, quiescent
state for the majority of pregnancy, before being transformed to a contractile and excitable …
state for the majority of pregnancy, before being transformed to a contractile and excitable …
Deletion of EP4 on bone marrow–derived cells enhances inflammation and angiotensin II–induced abdominal aortic aneurysm formation
EHC Tang, E Shvartz, K Shimizu… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—To examine whether a lack of prostaglandin E receptor 4 (EP4) on bone marrow–
derived cells would increase local inflammation and enhance the formation of abdominal …
derived cells would increase local inflammation and enhance the formation of abdominal …
Self-administered misoprostol or placebo before intrauterine device insertion in nulliparous women: a randomized controlled trial
OBJECTIVES: To estimate the effects of self-administered misoprostol compared with
placebo before intrauterine device (IUD) insertion in nulliparous women. METHOD …
placebo before intrauterine device (IUD) insertion in nulliparous women. METHOD …
Prostaglandin E and F receptors in the uterus
CS Blesson, L Sahlin - Receptors & Clinical Investigation, 2014 - smartscitech.com
Prostaglandins (PGs) are necessary for normal female reproduction. PGs act via their
respective receptors and execute various functions in their target tissues depending on …
respective receptors and execute various functions in their target tissues depending on …
[HTML][HTML] Prostaglandin receptors EP and FP are regulated by estradiol and progesterone in the uterus of ovariectomized rats
CS Blesson, E Büttner, B Masironi, L Sahlin - Reproductive biology and …, 2012 - Springer
Background Prostaglandins are important for female reproduction. Prostaglandin-E2 acts via
four different receptor subtypes, EP1, EP2, EP3 and EP4 whereas prostaglandin-F2alpha …
four different receptor subtypes, EP1, EP2, EP3 and EP4 whereas prostaglandin-F2alpha …
[HTML][HTML] IL-6 overexpression in ERG-positive prostate cancer is mediated by prostaglandin receptor EP2
C Merz, A Von Mässenhausen, A Queisser… - The American journal of …, 2016 - Elsevier
Prostate cancer is the most diagnosed cancer in men and multiple risk factors and genetic
alterations have been described. The TMPRSS2–ERG fusion event and the overexpression …
alterations have been described. The TMPRSS2–ERG fusion event and the overexpression …
Membrane Inflammasome activation by Choriodecidual Ureaplasma parvum infection without intra-amniotic infection in an NHP model
Intrauterine infection is a significant cause of preterm labor and neonatal morbidity and
mortality. Ureaplasma parvum is the microorganism most commonly isolated from cases of …
mortality. Ureaplasma parvum is the microorganism most commonly isolated from cases of …