[HTML][HTML] Biomaterials: foreign bodies or tuners for the immune response?
E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
to biomaterial implantation, despite the robustness of technologies that hold the promise to …
[HTML][HTML] Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases
Central nervous system (CNS) innate immunity plays essential roles in infections,
neurodegenerative diseases, and brain or spinal cord injuries. Astrocytes and microglia are …
neurodegenerative diseases, and brain or spinal cord injuries. Astrocytes and microglia are …
[HTML][HTML] Promoting tissue regeneration by modulating the immune system
The immune system plays a central role in tissue repair and regeneration. Indeed, the
immune response to tissue injury is crucial in determining the speed and the outcome of the …
immune response to tissue injury is crucial in determining the speed and the outcome of the …
Toll-like receptors: significance, ligands, signaling pathways, and functions in mammals
This review attempts to cover the implication of the toll-like receptors (TLRs) in controlling
immune functions with emphasis on their significance, function, regulation and expression …
immune functions with emphasis on their significance, function, regulation and expression …
[HTML][HTML] Heat shock proteins as immunomodulants
Heat shock proteins (Hsps) are conserved molecules whose main role is to facilitate folding
of other proteins. Most Hsps are generally stress-inducible as they play a particularly …
of other proteins. Most Hsps are generally stress-inducible as they play a particularly …
Fever and the thermal regulation of immunity: the immune system feels the heat
SS Evans, EA Repasky, DT Fisher - Nature Reviews Immunology, 2015 - nature.com
Fever is a cardinal response to infection that has been conserved in warm-blooded and cold-
blooded vertebrates for more than 600 million years of evolution. The fever response is …
blooded vertebrates for more than 600 million years of evolution. The fever response is …
Role of the immune system in hypertension
B Rodriguez-Iturbe, H Pons… - Physiological …, 2017 - journals.physiology.org
High blood pressure is present in more than one billion adults worldwide and is the most
important modifiable risk factor of death resulting from cardiovascular disease. While many …
important modifiable risk factor of death resulting from cardiovascular disease. While many …
Inflammation and the pathogenesis of atrial fibrillation
YF Hu, YJ Chen, YJ Lin, SA Chen - Nature Reviews Cardiology, 2015 - nature.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia. However, the development of
preventative therapies for AF has been disappointing. The infiltration of immune cells and …
preventative therapies for AF has been disappointing. The infiltration of immune cells and …
[HTML][HTML] HSP70 multi-functionality in cancer
Z Albakova, GA Armeev, LM Kanevskiy, EI Kovalenko… - Cells, 2020 - mdpi.com
The 70-kDa heat shock proteins (HSP70s) are abundantly present in cancer, providing
malignant cells selective advantage by suppressing multiple apoptotic pathways, regulating …
malignant cells selective advantage by suppressing multiple apoptotic pathways, regulating …
The role of toll‐like receptor 4 in infectious and noninfectious inflammation
M Molteni, S Gemma, C Rossetti - Mediators of inflammation, 2016 - Wiley Online Library
Toll‐like receptor 4 (TLR4) belongs to the family of pattern recognition receptors (PRRs).
They are highly conserved receptors that recognize conserved pathogen‐associated …
They are highly conserved receptors that recognize conserved pathogen‐associated …