Horizontal gene transfer among host-associated microbes

JM de Sousa, M Lourenço, I Gordo - Cell Host & Microbe, 2023 - cell.com
Horizontal gene transfer is an important evolutionary force, facilitating bacterial diversity. It is
thought to be pervasive in host-associated microbiomes, where bacterial densities are high …

Open questions in the social lives of viruses

A Leeks, LM Bono, EA Ampolini… - Journal of …, 2023 - academic.oup.com
Social interactions among viruses occur whenever multiple viral genomes infect the same
cells, hosts, or populations of hosts. Viral social interactions range from cooperation to …

The defense island repertoire of the Escherichia coli pan-genome

D Hochhauser, A Millman, R Sorek - PLoS genetics, 2023 - journals.plos.org
It has become clear in recent years that anti-phage defense systems cluster non-randomly
within bacterial genomes in so-called “defense islands”. Despite serving as a valuable tool …

Phage-inducible chromosomal minimalist islands (PICMIs), a novel family of small marine satellites of virulent phages

R Barcia-Cruz, D Goudenège… - Nature …, 2024 - nature.com
Phage satellites are bacterial genetic elements that co-opt phage machinery for their own
dissemination. Here we identify a family of satellites, named Phage-Inducible Chromosomal …

Anti-phage defence through inhibition of virion assembly

PH Patel, VL Taylor, C Zhang, LJ Getz… - Nature …, 2024 - nature.com
Bacteria have evolved diverse antiviral defence mechanisms to protect themselves against
phage infection. Phages integrated into bacterial chromosomes, known as prophages, also …

Simultaneous entry as an adaptation to virulence in a novel satellite-helper system infecting Streptomyces species

T deCarvalho, E Mascolo, SM Caruso… - The ISME …, 2023 - academic.oup.com
Satellites are mobile genetic elements that are dependent upon the replication machinery of
their helper viruses. Bacteriophages have provided many examples of satellite nucleic acids …

Dual pathogenicity island transfer by piggybacking lateral transduction

MSJ Chee, E Serrano, YN Chiang, J Harling-Lee… - Cell, 2023 - cell.com
Lateral transduction (LT) is the process by which temperate phages mobilize large sections
of bacterial genomes. Despite its importance, LT has only been observed during prophage …

A widespread family of phage-inducible chromosomal islands only steals bacteriophage tails to spread in nature

N Alqurainy, L Miguel-Romero, JM de Sousa, J Chen… - Cell Host & Microbe, 2023 - cell.com
Phage satellites are genetic elements that couple their life cycle to that of helper phages
they parasitize, interfering with phage packaging through the production of small capsids …

[HTML][HTML] Role of vertical and horizontal microbial transmission of antimicrobial resistance genes in early life: insights from maternal-infant dyads

M Bernabeu, E Cabello-Yeves, E Flores… - Current opinion in …, 2024 - Elsevier
Highlights•ARGs and MGEs are vertically trasferred from mothers to their offspring.•Antibiotic
exposure, C-section and lack of breastfeeding are risk factors for acquiring ARGs and …

A Vibrio cholerae viral satellite maximizes its spread and inhibits phage by remodeling hijacked phage coat proteins into small capsids

CM Boyd, S Subramanian, DT Dunham, KN Parent… - Elife, 2024 - elifesciences.org
Phage satellites commonly remodel capsids they hijack from the phages they parasitize, but
only a few mechanisms regulating the change in capsid size have been reported. Here, we …