[HTML][HTML] CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation

P Vasudevan, M Wolfien, H Lemcke, CI Lang… - Genome Medicine, 2023 - Springer
Background The immune response is a crucial factor for mediating the benefit of cardiac cell
therapies. Our previous research showed that cardiomyocyte transplantation alters the …

Reward system activation improves recovery from acute myocardial infarction

H Haykin, E Avishai, M Krot, M Ghiringhelli… - Nature Cardiovascular …, 2024 - nature.com
Psychological processes have a crucial role in the recovery from acute myocardial infarction
(AMI), yet the underlying mechanisms of these effects remain elusive. Here we demonstrate …

[HTML][HTML] Central Actions of Leptin Induce an Atrophic Pattern and Improves Heart Function in Lean Normoleptinemic Rats via PPARβ/δ Activation

B Rubio, C Pintado, L Mazuecos, M Benito, A Andrés… - Biomolecules, 2024 - mdpi.com
Leptin, acting centrally or peripherally, has complex effects on cardiac remodeling and heart
function. We previously reported that central leptin exerts an anti-hypertrophic effect in the …

[HTML][HTML] Multi-modal assessment of a cardiac stem cell therapy reveals distinct modulation of regional scar properties

M Schweins, R Gäbel, M Raitza, P Vasudevan… - Journal of Translational …, 2024 - Springer
Background The initial idea of functional tissue replacement has shifted to the concept that
injected cells positively modulate myocardial healing by a non-specific immune response of …

[HTML][HTML] Comparison of transient and permanent LAD ligation in mice using 18F-FDG PET imaging

M Fischer, T Weinberger, D Messerer… - Annals of Nuclear …, 2022 - Springer
Objective Animal models for myocardial injuries represent important cornerstones in
cardiovascular research to monitor the pathological processes and therapeutic approaches …

Microbeam irradiation of the beating rodent heart: An ex vivo study of acute and subacute effects on cardiac function

F Lange, T Kirschstein, J Davis, J Paino… - International Journal of …, 2022 - Elsevier
Purpose Microbeam radiation therapy (MRT) has shown several advantages compared with
conventional broad-beam radiation therapy in small animal models, including a better …

[HTML][HTML] Detection of apoptosis by [18F]ML-10 after cardiac ischemia–reperfusion injury in mice

M Fischer, MJ Zacherl, J Olivier, S Lindner… - Annals of Nuclear …, 2023 - Springer
Objective Myocardial infarction leads to ischemic heart disease and cell death, which is still
a major obstacle in western society. In vivo imaging of apoptosis, a defined cascade of cell …