The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential

X Meng, QY Lou, WY Yang, YR Wang… - Cancer …, 2021 - Wiley Online Library
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises
from the interaction of multiple factors including tobacco, alcohol consumption, and betel …

[HTML][HTML] NUPR1: a critical regulator of the antioxidant system

C Huang, P Santofimia-Castaño, J Iovanna - Cancers, 2021 - mdpi.com
Simple Summary Nuclear protein 1 (NUPR1) is activated in cellular stress and is expressed
at high levels in cancer cells. Much evidence has been gathered supporting its critical role in …

[HTML][HTML] NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy

T Fan, X Wang, S Zhang, P Deng, Y Jiang… - Signal transduction and …, 2022 - nature.com
Oral squamous cell carcinoma (OSCC) is the most common type of oral malignancy, and
metastasis accounts for the poor prognosis of OSCC. Autophagy is considered to facilitate …

The role of NUPR1 in response to stress and cancer development

S Liu, M Costa - Toxicology and Applied Pharmacology, 2022 - Elsevier
Stress contributes to the development of many human diseases, including cancer. Based on
the source of stress, it can be divided into external stress, such as environmental …

Cadmium promotes breast cancer cell proliferation, migration and invasion by inhibiting ACSS2/ATG5-mediated autophagy

Y Liang, H Pi, L Liao, M Tan, P Deng, Y Yue, Y Xi… - Environmental …, 2021 - Elsevier
Cadmium (Cd), which is considered a carcinogenic metal, promotes breast cancer (BC)
progression, but the precise mechanism remains unclear. Herein, MCF-7 and T47-D cells …

[HTML][HTML] Natural phytochemicals that affect autophagy in the treatment of oral diseases and infections: a review

X Cheng, Q Chen, P Sun - Frontiers in Pharmacology, 2022 - frontiersin.org
Autophagy is a critical factor in eukaryotic evolution. Cells provide nutrition and energy
during autophagy by destroying non-essential components, thereby allowing intracellular …

[HTML][HTML] Role of autophagy in the microenvironment of oral squamous cell carcinoma

D Peña-Oyarzún, M Reyes… - Frontiers in …, 2020 - frontiersin.org
Oral squamous cell carcinoma, the most common type of oral cancer, affects more than
275,000 people per year worldwide. Oral squamous cell carcinoma is very aggressive, as …

[HTML][HTML] Cadmium induces epithelial–mesenchymal transition and migration of renal cancer cells by increasing PGE2 through a cAMP/PKA-COX2 dependent …

H Shi, X Sun, A Kong, H Ma, Y Xie, D Cheng… - Ecotoxicology and …, 2021 - Elsevier
Environmental or occupational exposure of Cadmium (Cd) is concerned to be a threat to
human health. The kidney is main target of Cd accumulation, which increases the risk of …

The relationship between oral cancer and cadmium: a review

S Satir - Molecular Biology Reports, 2022 - Springer
Cadmium (Cd) has been classified as a type I carcinogen. Since it is ingested orally through
food and tobacco use, Cd is likely to be closely related to oral cancers. The relationship …

Cadmium toxicity and autophagy: a review

Y Shao, L Zheng, Y Jiang - Biometals, 2024 - Springer
Cadmium (Cd) is an important environmental pollutant that poses a threat to human health
and represents a critical component of air pollutants, food sources, and cigarette smoke. Cd …