[HTML][HTML] Microenvironment-Responsive Nanosystems for Osteoarthritis Therapy
S Li, Y Xiong, H Zhu, T Ma, X Sun, J Xiao - Engineered Regeneration, 2023 - Elsevier
Osteoarthritis (OA) represents an enduring and widespread global burden, causing
significant morbidity and disability, whose pathology is characterized by persistent …
significant morbidity and disability, whose pathology is characterized by persistent …
Polydopamine nanomaterials and their potential applications in the treatment of autoimmune diseases
The conventional treatment methods used for the management of autoimmune diseases
(ADs) have limited efficacy and also exhibit significant side effects. Thus, identification of …
(ADs) have limited efficacy and also exhibit significant side effects. Thus, identification of …
Mitochondrial-targeting and NIR-responsive Mn3O4@ PDA@ Pd-SS31 nanozymes reduce oxidative stress and reverse mitochondrial dysfunction to alleviate …
Y Li, J Yang, X Chen, H Hu, N Lan, J Zhao, L Zheng - Biomaterials, 2024 - Elsevier
Mitochondrial reactive oxygen species (mROS) play a crucial role in the process of
osteoarthritis (OA), which may be a promising target for therapy of OA. In this study, novel …
osteoarthritis (OA), which may be a promising target for therapy of OA. In this study, novel …
Curcumin-loaded mesoporous polydopamine nanoparticles modified by quaternized chitosan against bacterial infection through synergistic effect
X Han, W Gao, Z Zhou, Y Li, D Sun, H Gong… - International Journal of …, 2024 - Elsevier
Clinically, open wounds caused by accidental trauma and surgical lesion resection are
easily infected by external bacteria, hindering wound healing. Antibacterial photodynamic …
easily infected by external bacteria, hindering wound healing. Antibacterial photodynamic …
[HTML][HTML] Synergistic chemotherapy/PTT/oxygen enrichment by multifunctional liposomal polydopamine nanoparticles for rheumatoid arthritis treatment
X Fu, Y Song, X Feng, Z Liu, W Gao, H Song… - Asian Journal of …, 2024 - Elsevier
Amultifunctional liposomal polydopamine nanoparticle (MPM@ Lipo) was designed in this
study, to combine chemotherapy, photothermal therapy (PTT) and oxygen enrichment to …
study, to combine chemotherapy, photothermal therapy (PTT) and oxygen enrichment to …
Biocompatible copper formate-based nanoparticles with strong antibacterial properties for wound healing
Y Zhou, P Sun, Y Cao, J Yang, Q Wu, J Peng - Journal of …, 2023 - Springer
Copper-based antibacterial materials have emerged as a potential alternative for combating
bacterial infections, which continue to pose significant health risks. Nevertheless, the use of …
bacterial infections, which continue to pose significant health risks. Nevertheless, the use of …
[HTML][HTML] Isoorientin ameliorates H2O2-induced apoptosis and oxidative stress in chondrocytes by regulating MAPK and PI3K/Akt pathways
T Cui, Y Lan, Y Lu, F Yu, S Lin, Y Fu, J Qiu… - Aging (Albany NY …, 2023 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a chronic and complicated degenerative disease for which there is
currently no effective treatment. Isoorientin (ISO) is a natural plant extract that has …
currently no effective treatment. Isoorientin (ISO) is a natural plant extract that has …
Microneedle‐Delivered PDA@ Exo for Multifaceted Osteoarthritis Treatment via PI3K‐Akt‐mTOR Pathway
Z Li, H Lu, L Fan, X Ma, Z Duan, Y Zhang… - Advanced …, 2024 - Wiley Online Library
Osteoarthritis (OA) is marked by cartilage deterioration, subchondral bone changes, and an
inflammatory microenvironment. The study introduces the Microneedle‐Delivered …
inflammatory microenvironment. The study introduces the Microneedle‐Delivered …
Holmium (III)-doped multifunctional nanotheranostic agent for ultra-high-field magnetic resonance imaging-guided chemo-photothermal tumor therapy
R Zhang, M Liu, S Liu, X Liang, R Lu, X Shuai, D Wu… - Acta Biomaterialia, 2023 - Elsevier
Abstract Ultra-high-field (UHF) MRI has shown great advantages over low-field magnetic
resonance imaging (MRI). Despite being the most commonly used MRI contrast agents …
resonance imaging (MRI). Despite being the most commonly used MRI contrast agents …
Supramolecular 3 in 1: A Lubrication and Co-Delivery System for Synergistic Advanced Osteoarthritis Therapy
MM Chen, Y Li, Y Zhu, WC Geng, FY Chen, JJ Li… - ACS …, 2024 - ACS Publications
The complexity, heterogeneity, and drug resistance of diseases necessitate a shift in
therapeutic paradigms from monotherapy to combination therapy, which could augment …
therapeutic paradigms from monotherapy to combination therapy, which could augment …