Cranial neural crest cells are an evolutionary innovation of vertebrates for craniofacial
development and function, yet the mechanisms that govern the cell fate decisions of …

Mammalian embryogenesis commences with two pivotal and binary cell fate decisions that
give rise to three essential lineages: the trophectoderm, the epiblast and the primitive …

Early mammal embryogenesis starts with oocyte fertilization, giving rise to the zygote. The
events that the newly formed zygote surpasses are crucial to the embryo developmental …

Preimplantation development is well conserved across mammalian species, but major
differences in developmental kinetics, regulation of early lineage differentiation and …

The objective of this study was to evaluate the time of blastulation monitored by time-lapse
technology to predict in vitro viability of bovine blastocysts. This technology can be a …

Circular RNAs (circRNAs), which exert critical functions in the regulation of transcriptional
and post-transcriptional gene expression, are found in mammalian cells but their functions in …

Acquisition of new stem cell fates relies on the dissolution of the prior regulatory network
sustaining the existing cell fates. Currently, extensive insights have been revealed for the …

Epigenetic reprogramming of the parental genome is essential for zygotic genome activation
and subsequent embryo development in mammals. Asymmetric incorporation of histone H3 …

Circular RNAs (circRNAs) are a class of non-coding RNAs with diverse functions, and
previous studies have reported that circRNAs are involved in the growth and development of …

Mammalian preimplantation development is associated with marked metabolic robustness,
and embryos can develop under a wide variety of nutrient conditions, including even the …