Immune system involvement in specific pain conditions
SK Totsch, RE Sorge - Molecular pain, 2017 - journals.sagepub.com
Chronic pain is a significant problem worldwide and is the most common disability in the
United States. It is well known that the immune system plays a critical role in the …
United States. It is well known that the immune system plays a critical role in the …
Effects of betaine on LPS-stimulated activation of microglial M1/M2 phenotypes by suppressing TLR4/NF-κB pathways in N9 cells
H Shi, XL Wang, HF Quan, L Yan, XY Pei, R Wang… - Molecules, 2019 - mdpi.com
Microglia mediate multiple facets of neuroinflammation. They can be phenotypically divided
into a classical phenotype (pro-inflammatory, M1) or an alternative phenotype (anti …
into a classical phenotype (pro-inflammatory, M1) or an alternative phenotype (anti …
Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4/MyD88/NFκB signaling …
T Lwin, JL Yang, S Ngampramuan, K Viwatpinyo… - Progress in Neuro …, 2021 - Elsevier
Methamphetamine (METH) is a highly addictive psychostimulant that causes significant
health issues due to high prevalence of its illegal use. Chronic use of METH is associated …
health issues due to high prevalence of its illegal use. Chronic use of METH is associated …
[HTML][HTML] Alphalipoic acid prevents oxidative stress and peripheral neuropathy in nab-paclitaxel-treated rats through the Nrf2 signalling pathway
H Sun, X Guo, Z Wang, P Wang, Z Zhang… - … medicine and cellular …, 2019 - hindawi.com
Peripheral neuropathy is the major dose-limiting side effect of paclitaxel (PTX), affecting both
the quality of life and the survival of cancer patients. Nab-paclitaxel (nab-PTX) was …
the quality of life and the survival of cancer patients. Nab-paclitaxel (nab-PTX) was …
[HTML][HTML] Bidirectional action of cenicriviroc, a CCR2/CCR5 antagonist, results in alleviation of pain-related behaviors and potentiation of opioid analgesia in rats with …
K Kwiatkowski, K Pawlik, K Ciapała… - Frontiers in …, 2020 - frontiersin.org
Clinical management of neuropathic pain is unsatisfactory, mainly due to its resistance to the
effects of available analgesics, including opioids. Converging evidence indicates the …
effects of available analgesics, including opioids. Converging evidence indicates the …
Inhibition of interleukin-6 function attenuates the central sensitization and pain behavior induced by osteoarthritis
Y Lin, L Liu, H Jiang, J Zhou, Y Tang - European Journal of Pharmacology, 2017 - Elsevier
Chronic pain is the most prominent and disabling symptom in the patients with osteoarthritis
(OA), and the underlying mechanism largely remains unclear. Interleukin-6 (IL-6), a …
(OA), and the underlying mechanism largely remains unclear. Interleukin-6 (IL-6), a …
[PDF][PDF] Minocycline alleviated scopolamine-induced amnesia by regulating antioxidant and cholinergic function
MHE Ghalibaf, A Rajabian, M Parviz, M Akbarian… - Heliyon, 2023 - cell.com
Background and aim Minocycline, a tetracycline derivative, has been found to exert
neuroprotective properties. The current project aimed to assess the antioxidant status and …
neuroprotective properties. The current project aimed to assess the antioxidant status and …
[HTML][HTML] Sex dimorphism in resolvin D5-induced analgesia in rat models of trigeminal pain
DF Baggio, FMR da Luz, RV Lopes, LEN Ferreira… - The Journal of …, 2023 - Elsevier
Abstract Resolvin D5 (RvD5) is a specialized pro-resolving lipid mediator with potent anti-
inflammatory and analgesic properties. Orofacial pain conditions, especially those that are …
inflammatory and analgesic properties. Orofacial pain conditions, especially those that are …
[HTML][HTML] Sex differences in a double-blind randomized clinical trial with minocycline in treatment-resistant depressed patients: CRP and IL-6 as sex-specific predictors …
G Lombardo, MA Nettis, C Hastings… - Brain, Behavior, & …, 2022 - Elsevier
Background Inflammation is a well-known risk factor for depression. Specifically, patients
who do not respond to antidepressant treatment show higher levels of inflammatory …
who do not respond to antidepressant treatment show higher levels of inflammatory …
A correlative analysis between inflammatory cytokines and trigeminal neuralgia or hemifacial spasm
MX Liu, J Zhong, L Xia, NN Dou, ST Li - Neurological research, 2019 - Taylor & Francis
Background: It is necessary to understand the mechanism of trigeminal neuralgia (TN) and
hemifacial spasm (HFS) in order to seek for an effective noninvasive remedy. As previous …
hemifacial spasm (HFS) in order to seek for an effective noninvasive remedy. As previous …