Designing the next-generation clinical care pathway for Alzheimer's disease

H Hampel, R Au, S Mattke, WM van der Flier, P Aisen… - Nature Aging, 2022 - nature.com
The reconceptualization of Alzheimer's disease (AD) as a clinical and biological construct
has facilitated the development of biomarker-guided, pathway-based targeted therapies …

Management of sleep disturbances in Parkinson's disease

L Schütz, F Sixel-Döring… - Journal of Parkinson's …, 2022 - content.iospress.com
Parkinson's disease (PD) is defined by its motor symptoms rigidity, tremor, and akinesia.
However, non-motor symptoms, particularly autonomic disorders and sleep disturbances …

Effects of insomnia and restless legs syndrome on sleep arterial blood pressure: a systematic review and meta-analysis

G Maiolino, V Bisogni, D Soranna, MF Pengo… - Sleep medicine …, 2021 - Elsevier
Hypertension and blunted blood pressure (BP) dipping during nighttime sleep are
associated with increased cardiovascular risk. Chronic insomnia and restless legs syndrome …

Sleep–wake monitoring of people with intellectual disability: Examining the agreement of EMFIT QS and actigraphy

HP Buimer, NM Siebelink… - Journal of Applied …, 2023 - Wiley Online Library
Background Gaining insight into sleep–wake patterns of persons with intellectual disabilities
is commonly done using wrist actigraphy. For some people, contactless alternatives are …

Evaluation of a low-cost commercial actigraph and its potential use in detecting cultural variations in physical activity and sleep

P Topalidis, C Florea, ES Eigl, A Kurapov, CAB Leon… - Sensors, 2021 - mdpi.com
The purpose of the present study was to evaluate the performance of a low-cost commercial
smartwatch, the Xiaomi Mi Band (MB), in extracting physical activity and sleep-related …

Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART

AJ Ehrenberg, MA Kelberman, KY Liu… - Alzheimer's & …, 2023 - Wiley Online Library
The neuromodulatory subcortical system (NSS) nuclei are critical hubs for survival, hedonic
tone, and homeostasis. Tau‐associated NSS degeneration occurs early in Alzheimer's …

Objective sleep assessments for healthy people in environmental research: A literature review

X Xu, Z Lian - Indoor air, 2022 - Wiley Online Library
To date, although many studies had focused on the impact of environmental factors on
sleep, how to choose the proper assessment method for objective sleep quality was often …

Spectral Slope and Lempel–Ziv Complexity as Robust Markers of Brain States during Sleep and Wakefulness

C Höhn, MA Hahn, JD Lendner, K Hoedlmoser - Eneuro, 2024 - eneuro.org
Nonoscillatory measures of brain activity such as the spectral slope and Lempel–Ziv
complexity are affected by many neurological disorders and modulated by sleep. A multitude …

Automation of classification of sleep stages and estimation of sleep efficiency using actigraphy

H Kim, D Kim, J Oh - Frontiers in Public Health, 2023 - frontiersin.org
Introduction Sleep is a fundamental and essential physiological process for recovering
physiological function. Sleep disturbance or deprivation has been known to be a causative …

Sleep assessment in preterm infants: Use of actigraphy and aEEG

Ö Ülgen, HE Barış, ÖÖ Aşkan, SK Akdere, C Ilgın… - Sleep Medicine, 2023 - Elsevier
Objective Objective methods to monitor the sleep of preterm infants at the neonatal intensive
care unit (NICU) are required to prevent potentially adverse neurodevelopmental outcomes …