How early life stress impact maternal care: a systematic review of rodent studies

R Orso, KC Creutzberg, LE Wearick-Silva… - Frontiers in Behavioral …, 2019 - frontiersin.org
Background: Maternal care refers to the behavior performed by the dam to nourish and
protect her litter during its early development. Frequent and high-quality performance of …

A comprehensive approach to modeling maternal immune activation in rodents

MC Bucknor, A Gururajan, RC Dale… - Frontiers in …, 2022 - frontiersin.org
Prenatal brain development is a highly orchestrated process, making it a very vulnerable
window to perturbations. Maternal stress and subsequent inflammation during pregnancy …

[HTML][HTML] Social touch-like tactile stimulation activates a tachykinin 1-oxytocin pathway to promote social interactions

H Yu, W Miao, E Ji, S Huang, S Jin, X Zhu, MZ Liu… - Neuron, 2022 - cell.com
It is well known that affective and pleasant touch promotes individual well-being and
facilitates affiliative social communication, although the neural circuit that mediates this …

Social buffering of stress responses in nonhuman primates: Maternal regulation of the development of emotional regulatory brain circuits

MM Sanchez, KM McCormack, BR Howell - Social neuroscience, 2015 - Taylor & Francis
Social buffering, the phenomenon by which the presence of a familiar individual reduces or
even eliminates stress-and fear-induced responses, exists in different animal species and …

Sensitive periods of emotion regulation: influences of parental care on frontoamygdala circuitry and plasticity

DG Gee - New directions for child and adolescent development, 2016 - Wiley Online Library
Early caregiving experiences play a central role in shaping emotional development, stress
physiology, and refinement of limbic circuitry. Converging evidence across species …

[HTML][HTML] The importance of friendships in reducing brain responses to stress in adolescents exposed to childhood adversity: a preregistered systematic review

M Scheuplein, AL Van Harmelen - Current opinion in psychology, 2022 - Elsevier
Up to 50% of all children and adolescents growing up worldwide are exposed to at least one
form of childhood adversity (CA), which is one of the strongest predictors for later life …

A brain motivated to play: insights into the neurobiology of playfulness

SM Siviy - Behaviour, 2016 - brill.com
Play is an important part of normal childhood development and is seen in varied forms
among many mammals. While not indispensable to normal development, playful social …

Modeling prenatal opioid exposure in animals: current findings and future directions

EM Byrnes, FM Vassoler - Frontiers in neuroendocrinology, 2018 - Elsevier
The past decade has seen a drastic rise in the number of infants exposed to opioids in utero.
It is unclear what lasting effect this exposure may have on these children. Animal models of …

Serotonin transporter genotype modulates the gut microbiota composition in young rats, an effect augmented by early life stress

S El Aidy, AS Ramsteijn, F Dini-Andreote… - Frontiers in cellular …, 2017 - frontiersin.org
The neurotransmitter serotonin (5-HT) plays a vital regulatory role in both the brain and gut.
5-HT is crucial for regulating mood in the brain as well as gastrointestinal motility and …

Factors promoting vulnerability to dysregulated stress reactivity and stress‐related disease

AL Russell, JG Tasker, AB Lucion… - Journal of …, 2018 - Wiley Online Library
Effective coordination of the biological stress response is integral for the behavioural well‐
being of an organism. Stress reactivity is coordinated by an interplay of the neuroendocrine …