Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Intelligence is highly heritable and a major determinant of human health and well-being.
Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …
Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …
[HTML][HTML] Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …
with many important life outcomes. We combine cognitive and genetic data from the …
[HTML][HTML] A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence
Intelligence, or general cognitive function, is phenotypically and genetically correlated with
many traits, including a wide range of physical, and mental health variables. Education is …
many traits, including a wide range of physical, and mental health variables. Education is …
[HTML][HTML] Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income
Socioeconomic position (SEP) is a multi-dimensional construct reflecting (and influencing)
multiple socio-cultural, physical, and environmental factors. In a sample of 286,301 …
multiple socio-cultural, physical, and environmental factors. In a sample of 286,301 …
Decreases in brain size and encephalization in anatomically modern humans
JM Stibel - Brain, Behavior and Evolution, 2021 - karger.com
Growth in human brain size and encephalization is well documented throughout much of
prehistory and believed to be responsible for increasing cognitive faculties. Over the past …
prehistory and believed to be responsible for increasing cognitive faculties. Over the past …
[HTML][HTML] Genomic analysis of family data reveals additional genetic effects on intelligence and personality
Pedigree-based analyses of intelligence have reported that genetic differences account for
50–80% of the phenotypic variation. For personality traits these effects are smaller, with 34 …
50–80% of the phenotypic variation. For personality traits these effects are smaller, with 34 …
[HTML][HTML] A genome-wide association analysis identifies 16 novel susceptibility loci for carpal tunnel syndrome
Carpal tunnel syndrome (CTS) is a common and disabling condition of the hand caused by
entrapment of the median nerve at the level of the wrist. It is the commonest entrapment …
entrapment of the median nerve at the level of the wrist. It is the commonest entrapment …
Genomic updates in understanding PTSD
S Sharma, KJ Ressler - Progress in Neuro-Psychopharmacology and …, 2019 - Elsevier
Twin studies as well as more recent genetics-based heritability analyses demonstrate that
up to 40 to 50% of the variance in predicting PTSD following trauma is heritable. However …
up to 40 to 50% of the variance in predicting PTSD following trauma is heritable. However …
[HTML][HTML] Age and cognitive decline in the UK Biobank
MC Cornelis, Y Wang, T Holland, P Agarwal… - PLoS …, 2019 - journals.plos.org
Objectives Age-related cognitive decline is a well-known phenomenon after age 65 but little
is known about earlier changes and prior studies are based on relatively small samples. We …
is known about earlier changes and prior studies are based on relatively small samples. We …
[HTML][HTML] Resting-state connectivity and its association with cognitive performance, educational attainment, and household income in the UK Biobank
Background Cognitive ability is an important predictor of lifelong physical and mental well-
being, and impairments are associated with many psychiatric disorders. Higher cognitive …
being, and impairments are associated with many psychiatric disorders. Higher cognitive …