[HTML][HTML] The history of pertussis toxin

C Locht, R Antoine - Toxins, 2021 - mdpi.com
Besides the typical whooping cough syndrome, infection with Bordetella pertussis or
immunization with whole-cell vaccines can result in a wide variety of physiological …

[HTML][HTML] Evaluation of whole-cell and acellular pertussis vaccines in the context of long-term herd immunity

E Szwejser-Zawislak, MM Wilk, P Piszczek, J Krawczyk… - Vaccines, 2022 - mdpi.com
After the pertussis vaccine had been introduced in the 1940s and was shown to be very
successful in reducing the morbidity and mortality associated with the disease, the possibility …

Immunogenicity and safety of BPZE1, an intranasal live attenuated pertussis vaccine, versus tetanus–diphtheria–acellular pertussis vaccine: a randomised, double …

C Keech, VE Miller, B Rizzardi, C Hoyle, MJ Pryor… - The Lancet, 2023 - thelancet.com
Background Bordetella pertussis epidemics persist as transmission remains unabated
despite high acellular pertussis vaccination rates. BPZE1, a live attenuated intranasal …

[HTML][HTML] Effective and safe transfer of maternal antibodies persisting two months postpartum following maternal immunization with different doses of recombinant …

K Chokephaibulkit, T Puthanakit… - Vaccine, 2024 - Elsevier
Introduction Recombinant acellular pertussis (ap) vaccines containing genetically
inactivated pertussis toxin (PT gen) and filamentous hemagglutinin (FHA) with or without …

Antibody and B-cell immune responses against Bordetella pertussis following infection and immunization

B Abu-Raya, MJ Esser, E Nakabembe, J Reiné… - Journal of molecular …, 2023 - Elsevier
Neither immunization nor recovery from natural infection provides life-long protection
against Bordetella pertussis. Replacement of a whole-cell pertussis (wP) vaccine with an …

[HTML][HTML] The whole-cell pertussis vaccine imposes a broad effector B cell response in mouse heterologous prime-boost settings

V Valeri, A Sochon, C Cousu, P Chappert… - JCI insight, 2022 - ncbi.nlm.nih.gov
ÍSince the introduction of new generation pertussis vaccines, resurgence of pertussis has
been observed in many developed countries. Former whole-cell pertussis (wP) vaccines are …

[HTML][HTML] A phase 2 randomized controlled dose-ranging trial of recombinant pertussis booster vaccines containing genetically inactivated pertussis toxin in women of …

K Chokephaibulkit, T Puthanakit, N Bhat, S Mansouri… - Vaccine, 2022 - Elsevier
Background A phase 2 randomized-controlled safety and immunogenicity trial evaluating
different doses of recombinant acellular pertussis vaccine containing genetically-inactivated …

[HTML][HTML] Pasteurian Contributions to the Study of Bordetella pertussis Toxins

C Locht - Toxins, 2023 - mdpi.com
As a tribute to Louis Pasteur on the occasion of the 200th anniversary of his birth, this article
summarizes the main contributions of scientists from Pasteur Institutes to the current …

[HTML][HTML] A phase 2 randomized controlled dose-ranging trial of recombinant pertussis booster vaccines containing genetically inactivated pertussis toxin in pregnant …

T Puthanakit, K Chokephaibulkit… - Vaccine, 2023 - Elsevier
Introduction Despite a decrease in infections caused by Bordetella pertussis due to COVID-
19 pandemic, booster vaccination of pregnant women is still recommended to protect …

[HTML][HTML] Transplacental transfer of maternal antibodies following immunization with recombinant pertussis vaccines during pregnancy: Real-world evidence

S Chaithongwongwatthana, W Wijagkanalan… - International Journal of …, 2024 - Elsevier
Aim/objective This study investigates placental antibody transfer following recombinant
pertussis vaccination in pregnancy in a real-world setting. Methods This postmarketing …