There is an urgent need to identify novel therapies for childhood cancers. Neuroblastoma is
the most common pediatric solid tumor, and accounts for~ 15% of childhood cancer‐related …

Flavonoids are a major group of phytoestrogens associated with physiological effects, and
ecological and social impacts. Although the estrogenic activity of flavonoids was reported by …

Abstract The Zero Childhood Cancer Program is a precision medicine program to benefit
children with poor-outcome, rare, relapsed or refractory cancer. Using tumor and germline …

Medulloblastoma, a malignant childhood cerebellar tumour, segregates molecularly into
biologically distinct subgroups, suggesting that a personalized approach to therapy would …

Modern computer vision algorithms are based on convolutional neural networks (CNNs),
and both end-to-end learning and transfer learning modes have been used with CNN for …

Intratumour heterogeneity is a major cause of treatment failure in cancer. We present in-
depth analyses combining transcriptomic and genomic profiling with ultra-deep targeted …

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, and can be
subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last …

Abstract Background and Purpose To enable accurate magnetic resonance imaging (MRI)-
based dose calculations, synthetic computed tomography (sCT) images need to be …

Simple Summary Childhood cancers are mostly of unknown etiology and represent
devastating diagnoses. The clinical benefits of steadily increasing tumor control and survival …

Osteosarcoma (OS) is the most serious bone malignancy, and the survival rate has not
significantly improved in the past 40 years. Thus, it is urgent to develop a new strategy for …