Postcontraction [acetylcarnitine] reflects interindividual variation in skeletal muscle ATP production patterns in vivo

CMT Hayden, R Nagarajan, ZH Smith… - American Journal …, 2024 - journals.physiology.org
In addition to its role in substrate selection (carbohydrate vs. fat) for oxidative metabolism in
muscle, acetylcarnitine production may be an important modulator of the energetic pathway …

Rates of oxidative ATP synthesis are not augmented beyond the pH threshold in human vastus lateralis muscles during a stepwise contraction protocol

MF Bartlett, LF Fitzgerald, JA Kent - The Journal of physiology, 2021 - Wiley Online Library
Key points The oxygen cost of high‐intensity exercise at power outputs above an individual's
lactate threshold (LT) is greater than would be predicted by the linear oxygen consumption …

Measurements of in vivo skeletal muscle oxidative capacity are lower following sustained isometric compared with dynamic contractions

MF Bartlett, LF Fitzgerald… - Applied Physiology …, 2023 - cdnsciencepub.com
Human skeletal muscle oxidative capacity can be quantified non-invasively using 31-
phosphorus magnetic resonance spectroscopy (31P-MRS) to measure the rate constant of …

Effects of old age and contraction mode on knee extensor muscle ATP flux and metabolic economy in vivo

LF Fitzgerald, MF Bartlett, R Nagarajan… - The Journal of …, 2021 - Wiley Online Library
Key points We used 31‐phosphorus magnetic resonance spectroscopy to quantify in vivo
skeletal muscle metabolic economy (ME; mass‐normalized torque or power produced per …

Muscle fatigue, bioenergetic responses and metabolic economy during load‐and velocity‐based maximal dynamic contractions in young and older adults

LF Fitzgerald, MF Bartlett, JA Kent - Physiological Reports, 2023 - Wiley Online Library
We evaluated whether task‐dependent, age‐related differences in muscle fatigue
(contraction‐induced decline in normalized power) develop from differences in …