Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications

A Caturano, M D'Angelo, A Mormone, V Russo… - Current Issues in …, 2023 - mdpi.com
Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …

Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress, and …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen …

C Tu, H Lu, T Zhou, W Zhang, L Deng, W Cao, Z Yang… - Biomaterials, 2022 - Elsevier
The diabetic wound is easily to develop into a chronic wound because of the extremely
serious and complex inflammatory microenvironment including biofilm formation, over …

Insulin resistance and cardiovascular disease

CE Kosmas, MD Bousvarou… - Journal of …, 2023 - journals.sagepub.com
Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …

Pharmaceutical drugs and natural therapeutic products for the treatment of type 2 diabetes mellitus

J Blahova, M Martiniakova, M Babikova, V Kovacova… - Pharmaceuticals, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the most widespread form of diabetes, characterized by
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …

[HTML][HTML] Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress

PV Dludla, SE Mabhida, K Ziqubu… - World journal of …, 2023 - ncbi.nlm.nih.gov
Insulin resistance and pancreatic β-cell dysfunction are major pathological mechanisms
implicated in the development and progression of type 2 diabetes (T2D). Beyond the …

[HTML][HTML] The long history of vitamin C: from prevention of the common cold to potential aid in the treatment of COVID-19

G Cerullo, M Negro, M Parimbelli, M Pecoraro… - Frontiers in …, 2020 - frontiersin.org
From Pauling's theories to the present, considerable understanding has been acquired of
both the physiological role of vitamin C and of the impact of vitamin C supplementation on …

Mechanisms underlying the pathophysiology of type 2 diabetes: From risk factors to oxidative stress, metabolic dysfunction, and hyperglycemia

JEBF Lima, NCS Moreira, ET Sakamoto-Hojo - Mutation Research/Genetic …, 2022 - Elsevier
Abstract Type 2 diabetes (T2D) is a complex multifactorial disease that emerges from the
combination of genetic and environmental factors, and obesity, lifestyle, and aging are the …

[HTML][HTML] Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes

M Flensted-Jensen, M Gram, F Dela, JW Helge… - Free Radical Biology …, 2021 - Elsevier
Obesity has been associated with increased production of reactive oxygen species (ROS),
which may be involved in the development of cardiovascular disease and type 2 diabetes …

The influence of lifestyle and treatment on oxidative stress and inflammation in diabetes

M Wronka, J Krzemińska, E Młynarska, J Rysz… - International Journal of …, 2022 - mdpi.com
Diabetes is considered a new pandemic of the modern world, and the number of sufferers is
steadily increasing. Sustained hyperglycemia promotes the production of free radicals and …