[HTML][HTML] Mechanisms of primary membranous nephropathy

Y Gu, H Xu, D Tang - Biomolecules, 2021 - mdpi.com
Membranous nephropathy (MN) is an autoimmune disease of the kidney glomerulus and
one of the leading causes of nephrotic syndrome. The disease exhibits heterogenous …

[HTML][HTML] Autoantibodies in the diagnosis, monitoring, and treatment of membranous nephropathy

V Tesar, Z Hruskova - Frontiers in Immunology, 2021 - frontiersin.org
The discovery of anti-podocyte antibodies in primary membranous nephropathy (MN) has
revolutionized our approach toward the diagnosis and treatment of this disease. Evaluation …

[HTML][HTML] Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry

TN Caza, AJ Storey, SI Hassen, C Herzog… - Kidney International, 2023 - Elsevier
Multiple autoantigens have been identified in membranous nephropathy (MN) by tissue-
based proteomics. However, antigenic targets of disease are unknown for over 10% of …

[HTML][HTML] A target antigen–based approach to the classification of membranous nephropathy

SA Bobart, S Tehranian, S Sethi, MP Alexander… - Mayo Clinic …, 2021 - Elsevier
Objective To describe the clinical and pathological phenotype of membranous nephropathy
(MN) associated with M-type-phospholipase–A 2-receptor (PLA 2 R), thrombospondin-type …

[HTML][HTML] Idiopathic membranous nephropathy: glomerular pathological pattern caused by extrarenal immunity activity

W Liu, C Gao, Z Liu, H Dai, Z Feng, Z Dong… - Frontiers in …, 2020 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is a pathological pattern of glomerular damage
caused by an autoimmune response. Immune complex deposition, thickness of glomerular …

[HTML][HTML] Novel biomarkers in membranous nephropathy

Q Liu, J Liu, B Lin, Y Zhang, M Ma, M Yang… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the main cause of adult nephrotic syndrome (NS). The
pathogenesis of MN is complex and involves subepithelial immune complex deposition …

[HTML][HTML] How times have changed! A cornucopia of antigens for membranous nephropathy

TN Caza, LF Al-Rabadi, LH Beck Jr - Frontiers in Immunology, 2021 - frontiersin.org
The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the
majority of primary (idiopathic) cases of membranous nephropathy (MN) has been followed …

[HTML][HTML] Definition of IgG subclass-specific glycopatterns in idiopathic membranous nephropathy: Aberrant IgG glycoforms in blood

C Chinello, N de Haan, G Capitoli, B Trezzi… - International Journal of …, 2022 - mdpi.com
The podocyte injury, and consequent proteinuria, that characterize the pathology of
idiopathic membranous nephropathy (IMN) is mediated by an autoimmune reaction against …

[HTML][HTML] The Onco-Nephrology Field: The Role of Personalized Chemotherapy to Prevent Kidney Damage

A Noce, G Marrone, M Di Lauro, AP Mitterhofer… - Cancers, 2023 - mdpi.com
Simple Summary The onco-nephrology field: the interaction between cancer and kidney
disease emphasizes the nephrology–oncology connection. This narrative review focuses on …

Revisiting immunological and clinical aspects of membranous nephropathy

I Nieto-Gañán, I Iturrieta-Zuazo, C Rita… - Clinical …, 2022 - Elsevier
Idiopathic or primary membranous nephropathy (IMN) is one of the most frequent causes of
nephrotic syndrome in adults and the elderly. It is characterized by a thickening of the wall of …