Keloids constitute an abnormal fibroproliferative wound healing response in which raised
scar tissue grows excessively and invasively beyond the original wound borders. This …

Although hypertrophic scars and keloids both generate excessive scar tissue, keloids are
characterized by their extensive growth beyond the borders of the original wound, which is …

Keloids are locally aggressive scars that typically invade into healthy surrounding skin and
cause both physical and psychosocial distress to the patient. These pathological scars occur …

Hypertrophic scars and keloids are firm, raised, erythematous plaques or nodules that
manifest when the cicatrix fails to properly heal. They result from pathologic wound healing …

In order to identify a means to reduce scar formation of the skin after incision, this study
examined the effect of local administration of basic fibroblast growth factor (bFGF) in …

Background Numerous treatments have been attempted with unsatisfactory results using
either single or combination modalities for treatment of keloids and hypertrophic scars. The …

The purpose of this study was to identify microRNAs (miRNAs) involved in keloid formation
and determine their influence on the proliferation of keloid fibroblasts (KFs). Eight specimens …

Although recent clinical reports have indicated that recombinant basic fibroblast growth
factor (bFGF) promotes scarless wound healing, the mechanism remains unclear. The …

Background Keloid scarring is a dermal fibroproliferative disorder characterized by
increased fibroblast proliferation and excessive production of collagen and extracellular …

Particle-induced osteolysis is a major cause of aseptic loosening after total joint
replacement. The purpose of the current study was to identify various apoptosis-related …