Effect of Plasmodium falciparum sulfadoxine-pyrimethamine resistance on the effectiveness of intermittent preventive therapy for malaria in pregnancy in Africa: a …
AM van Eijk, DA Larsen, K Kayentao… - The Lancet Infectious …, 2019 - thelancet.com
Summary Background Resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine
threatens the antimalarial effectiveness of intermittent preventive treatment during …
threatens the antimalarial effectiveness of intermittent preventive treatment during …
Advances in nanomedicines for malaria treatment
NP Aditya, PG Vathsala, V Vieira, RSR Murthy… - Advances in colloid and …, 2013 - Elsevier
Malaria is an infectious disease that mainly affects children and pregnant women from
tropical countries. The mortality rate of people infected with malaria per year is enormous …
tropical countries. The mortality rate of people infected with malaria per year is enormous …
Introducing BASE: the Biomes of Australian Soil Environments soil microbial diversity database
Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …
RAiSD detects positive selection based on multiple signatures of a selective sweep and SNP vectors
N Alachiotis, P Pavlidis - Communications biology, 2018 - nature.com
Selective sweeps leave distinct signatures locally in genomes, enabling the detection of loci
that have undergone recent positive selection. Multiple signatures of a selective sweep are …
that have undergone recent positive selection. Multiple signatures of a selective sweep are …
Selection and spread of artemisinin-resistant alleles in Thailand prior to the global artemisinin resistance containment campaign
E Talundzic, SA Okoth, K Congpuong… - PLoS …, 2015 - journals.plos.org
The recent emergence of artemisinin resistance in the Greater Mekong Subregion poses a
major threat to the global effort to control malaria. Tracking the spread and evolution of …
major threat to the global effort to control malaria. Tracking the spread and evolution of …
Evolution of Plasmodium falciparum drug resistance: implications for the development and containment of artemisinin resistance
T Mita, K Tanabe - Japanese journal of infectious diseases, 2012 - jstage.jst.go.jp
Malaria is a protozoan disease transmitted by the bite of the Anopheles mosquito. Among
five species that can infect humans, Plasmodium falciparum is responsible for the most …
five species that can infect humans, Plasmodium falciparum is responsible for the most …
Emerging implications of policies on malaria treatment: genetic changes in the Pfmdr-1 gene affecting susceptibility to artemether–lumefantrine and artesunate …
LC Okell, LM Reiter, LS Ebbe, V Baraka, D Bisanzio… - BMJ global …, 2018 - gh.bmj.com
Artemether–lumefantrine (AL) and artesunate–amodiaquine (AS-AQ) are the most
commonly used artemisinin-based combination therapies (ACT) for treatment of …
commonly used artemisinin-based combination therapies (ACT) for treatment of …
Efficacy of artemether–lumefantrine, artesunate–amodiaquine, and dihydroartemisinin–piperaquine for treatment of uncomplicated Plasmodium falciparum malaria in …
MM Plucinski, PR Dimbu, AP Macaia, CM Ferreira… - Malaria Journal, 2017 - Springer
Background Recent anti-malarial resistance monitoring in Angola has shown efficacy of
artemether–lumefantrine (AL) in certain sites approaching the key 90% lower limit of efficacy …
artemether–lumefantrine (AL) in certain sites approaching the key 90% lower limit of efficacy …
Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance
L Von Seidlein, A Dondorp - Expert review of anti-infective therapy, 2015 - Taylor & Francis
The emergence and spread of antimalarial resistance has been a major liability for malaria
control. The spread of chloroquine-resistant Plasmodium falciparum strains had catastrophic …
control. The spread of chloroquine-resistant Plasmodium falciparum strains had catastrophic …
High prevalence of Pfdhfr–Pfdhps quadruple mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Bioko Island …
T Jiang, J Chen, H Fu, K Wu, Y Yao, JUM Eyi… - Malaria journal, 2019 - Springer
Background Sulfadoxine–pyrimethamine (SP) is recommended for intermittent preventive
treatment of malaria in Africa. However, increasing SP resistance (SPR) affects the …
treatment of malaria in Africa. However, increasing SP resistance (SPR) affects the …