Circadian regulation of genetic and hormonal risk factors of cardiovascular disease in women
I Rabinovich-Nikitin, M Crandall… - Canadian Journal of …, 2022 - cdnsciencepub.com
Cardiovascular disease is the leading cause of morbidity and mortality worldwide. However,
sex differences can impact differently the etiology and outcome of cardiovascular disease …
sex differences can impact differently the etiology and outcome of cardiovascular disease …
[HTML][HTML] Female sex hormone effects on the vasculature: considering the validity of restricting study inclusion to low-hormone phases
Many studies of vascular function limit the testing of premenopausal female participants to
periods when female sex hormones, either endogenous or exogenous, are at their lowest …
periods when female sex hormones, either endogenous or exogenous, are at their lowest …
Tanshinone IIA prevents Leu27IGF-II-induced cardiomyocyte hypertrophy mediated by estrogen receptor and subsequent Akt activation
YS Weng, HF Wang, PY Pai, GP Jong… - The American journal …, 2015 - World Scientific
IGF-IIR plays important roles as a key regulator in myocardial pathological hypertrophy and
apoptosis, which subsequently lead to heart failure. Salvia miltiorrhiza Bunge (Danshen) is a …
apoptosis, which subsequently lead to heart failure. Salvia miltiorrhiza Bunge (Danshen) is a …
Estrogen protects the female heart from ischemia/reperfusion injury through manganese superoxide dismutase phosphorylation by mitochondrial p38β at threonine 79 …
T Luo, H Liu, JK Kim - PloS one, 2016 - journals.plos.org
A collective body of evidence indicates that estrogen protects the heart from myocardial
ischemia/reperfusion (I/R) injury, but the underlying mechanism remains incompletely …
ischemia/reperfusion (I/R) injury, but the underlying mechanism remains incompletely …
Sex differences in animal models for cardiovascular diseases and the role of estrogen
S Mahmoodzadeh, D Fliegner, E Dworatzek - Sex and Gender Differences …, 2012 - Springer
Clinical findings show sex differences in the manifestation of a number of cardiovascular
diseases (CVD). However, the underlying molecular mechanisms are incompletely …
diseases (CVD). However, the underlying molecular mechanisms are incompletely …
Mechanism of cardioprotection: what can we learn from females?
E Murphy, C Lagranha, A Deschamps, M Kohr… - Pediatric …, 2011 - Springer
This review examines the mechanism of estrogen signaling in cardiomyocytes, with an
emphasis on mechanisms that might be important in cardioprotection. It investigates …
emphasis on mechanisms that might be important in cardioprotection. It investigates …
The effect of gender combinations on outcome in human lung transplantation: the International Society of Heart and Lung Transplantation Registry experience
BACKGROUND: In the current practice of lung transplantation, donor and recipient genders
are neither directly considered nor matched. METHODS: We analyzed the potential effect of …
are neither directly considered nor matched. METHODS: We analyzed the potential effect of …
Estrogen receptor β agonism increases survival in experimentally induced sepsis and ameliorates the genomic sepsis signature: a pharmacogenomic study
E Christaki, SM Opal, JC Keith Jr… - The Journal of …, 2010 - academic.oup.com
Background. Nonsteroidal agonists have been developed that selectively bind to and
activate estrogen receptor β (ERβ) rather than estrogen receptor a (ERα). ERβ is expressed …
activate estrogen receptor β (ERβ) rather than estrogen receptor a (ERα). ERβ is expressed …
Sex hormone control of left ventricular structure/function: mechanistic insights using echocardiography, expression, and DNA methylation analyses in adult mice
IA Sebag, MA Gillis, A Calderone… - American Journal …, 2011 - journals.physiology.org
Calcium flux into and out of the sarco (endo) plasmic reticulum is vitally important to cardiac
function because the cycle of calcium entry and exit controls contraction and relaxation …
function because the cycle of calcium entry and exit controls contraction and relaxation …
Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER) α agonist and unaffected by an ERβ antagonist
HL Jeanes, C Tabor, D Black… - The Journal of …, 2008 - joe.bioscientifica.com
Oestrogen protects the heart from ischaemic injury. The current study aims to characterise
two novel oestrogen receptor (ER) ligands, an ERa agonist ERA-45 and an ERb antagonist …
two novel oestrogen receptor (ER) ligands, an ERa agonist ERA-45 and an ERb antagonist …