Interleukin (IL)-4 and-13 are structurally and functionally related cytokines sharing common
receptor subunits. They regulate immune responses and, moreover, are involved in the …

Colorectal cancer (CRC) is known as one of the deadliest and most common cancers
globally and causes nearly one million cancer deaths yearly. Like many malignancies, the …

Interferons (IFNs) are proteins involved in many functions including antiviral and
antimicrobial response, apoptosis, cell cycle control and mediating other cytokines. IFN …

Interleukins are a group of cytokines that contribute to growth and differentiation, cell
migration, and inflammatory and anti‐inflammatory responses by the immune system. In our …

In previous pre-clinical studies, we examined the contribution of interleukin 4 receptor (IL4R)
signaling in the progression and metastasis of colorectal cancer (CRC). Aberrant activation …

Background Previous studies have suggested that IL4, IL13, and IL4R are associated with
serum IgE levels and allergies, and common variants of these genes may alter cancer risk …

Supplementary Table 1. Association of SNPs with colorectal cancer based on logistic
regression model in 687 Korean men in the KCPS-II Chr rs no. Position Gene/Locus a A1 A2 …

Purpose Natural killer cells (NK cells) play important roles in protecting the patient from the
early development of cancers, and are activated or inhibited by killer cell immunoglobulin …

The previous studies found that chronic inflammation related to an increased risk of
colorectal cancer (CRC). This study aims to explore the associations of polymorphisms in …

We investigated the role of interleukin (IL)-4 receptor (IL-4R) signalling during mouse
carcinogen-induced colorectal carcinogenesis and in a case–control genetic …