Neurodevelopmental neuropsychiatric disorders, such as autism spectrum disorder and
schizophrenia, have strong genetic risk components, but the underlying mechanisms have …

Our genetic makeup, together with environmental and social influences, shape our brain's
development. Yet, the imaging genetics field has struggled to integrate all these modalities …

Abstract Development in domains like motor ability, thinking and learning, social abilities,
and communication are important areas of concern for individuals affected by genetic …

Copy number variations (CNVs) are genetic variants that can have a substantial influence
on neurodevelopment, neuropsychiatric traits, and morphometric brain changes, yet their …

Neurodevelopmental conditions (or neurodevelopmental disorders, NDDs) are highly
heterogeneous with overlapping characteristics and shared genetic etiology. The large …

Although rare neurodevelopmental conditions have a large Mendelian component, common
genetic variants also contribute to risk. However, little is known about how this polygenic risk …

Recent studies have indicated that some phenotypes caused by decreased function of
select neurodevelopmental disorder (NDD) risk genes can be reversed by restoring gene …

There is long-standing evidence that in adults a genetic overlap exists in risk between
autism spectrum disorder (ASD), schizophrenia, and intellectual disability (1, 2). A range of …

Do different genetic disorders impart different psychiatric risk profiles? This question has
major implications for biological and translational aspects of psychiatry, but has been difficult …

There is a growing interest in using machine learning (ML) models to perform automatic
diagnosis of psychiatric conditions; however, generalising the prediction of ML models to …