Tyrosine-kinase inhibitors have changed the natural history of chronic myeloid leukaemia in
such a way that patients with adequate access to these agents, who are properly managed …

Chronic myeloid leukemia (CML) is defined by the presence of Philadelphia chromosome
resulting from a reciprocal translocation between chromosomes 9 and 22 [t9; 22] that gives …

Introduction TKIs are paradigmatic in CML management and offer patients the prospect of a
normal life expectancy. As a consequence, the focus of both the clinician and patient has …

The management of chronic myeloid leukemia (CML) diagnosed during pregnancy is a rare
and challenging situation. We report the treatment and outcome of 87 cases diagnosed in …

Since the introduction of tyrosine kinase inhibitors (TKIs) at the beginning of the millennium,
the outlook for patients with chronic myeloid leukemia (CML) has improved remarkably. As …

Purpose Despite the general recommendation to avoid Tyrosine Kinase Inhibitors (TKIs) for
Chronic Myeloid Leukemia (CML) during pregnancy, unplanned pregnancies still occur …

Tyrosine kinase inhibitors (TKI) have improved the outcome and life expectancy of patients
with chronic myeloid leukemia (CML). Patients are diagnosed with CML at younger ages …

Chronic myeloid leukemia (CML) management during pregnancy is challenging. In this
retrospective study, hospital records of CML patients treated between 2000 and 2021 were …

Objective The purpose of this meta-analysis was to assess the safety of the anti-thyroid
drugs (ATDs) propylthiouracil (PTU) and methimazole (MMI) in the treatment of …

The overwhelming success of tyrosine kinase inhibitor (TKI) therapy in chronic myeloid
leukemia (CML) patients has opened a discussion among medical practitioners and the lay …