Abstract Adoption of Quality by Design (QbD) principles, regulatory support of QbD, process
analytical technology (PAT), and continuous manufacturing are major factors effecting new …

Organism-level systems biology aims to identify, analyze, control and design cellular circuits
in organisms. Many experimental and computational approaches have been developed …

A survey of the literature is presented that provides an analysis of the optical properties of
human skin, with particular regard to their applications in medicine. Included is a description …

Polarization is a fundamental property of light and a powerful sensing tool that has been
applied to many areas. A Mueller matrix is a complete mathematical description of the …

Skin-attachable sensors, which represent the ultimate form of wearable electronic devices
that ensure conformal contact with skin, suffer from motion artifact limitations owing to …

Recently, with the emergence of new light sources, polarization devices, and detectors,
together with a prominent increase in data processing capability, polarization techniques …

A thorough understanding of optical properties of biological tissues is critical to effective
treatment planning for therapies such as photodynamic therapy (PDT). In the last two …

We demonstrate three-dimensional (3D) super-resolution live-cell imaging through thick
specimens (50–150 μm), by coupling far-field individual molecule localization with selective …

Gold nanoparticles targeting epidermal growth factor receptor via antibody conjugation
undergo molecular specific aggregation when they bind to receptors on cell surfaces …

Noninvasive and real-time analysis of skin properties is useful in a wide variety of
applications. In particular, the quantitative assessment of skin in terms of hemoglobin and …