[HTML][HTML] Nanotechnology advances in the detection and treatment of cancer: an overview
Over the last few years, progress has been made across the nanomedicine landscape, in
particular, the invention of contemporary nanostructures for cancer diagnosis and …
particular, the invention of contemporary nanostructures for cancer diagnosis and …
[HTML][HTML] Metastasis and MAPK pathways
M Kciuk, A Gielecińska, A Budzinska… - International journal of …, 2022 - mdpi.com
Cancer is a leading cause of death worldwide. In many cases, the treatment of the disease is
limited due to the metastasis of cells to distant locations of the body through the blood and …
limited due to the metastasis of cells to distant locations of the body through the blood and …
[HTML][HTML] Targeting cancer stem cells as the key driver of carcinogenesis and therapeutic resistance
The emerging concept of cancer stem cells (CSCs) as the key driver behind carcinogenesis,
progression, and diversity has displaced the prior model of a tumor composed of cells with …
progression, and diversity has displaced the prior model of a tumor composed of cells with …
[HTML][HTML] Cancer cell cycle heterogeneity as a critical determinant of therapeutic resistance
Intra-tumor heterogeneity is now arguably one of the most-studied topics in tumor biology, as
it represents a major obstacle to effective cancer treatment. Since tumor cells are highly …
it represents a major obstacle to effective cancer treatment. Since tumor cells are highly …
[HTML][HTML] Unveiling the mechanisms and challenges of cancer drug resistance
Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer
treatment strategies are evolving due to innate and acquired resistance capacity, governed …
treatment strategies are evolving due to innate and acquired resistance capacity, governed …
[HTML][HTML] Cancer stem cells and the tumor microenvironment: targeting the critical crosstalk through nanocarrier systems
A Nayak, NM Warrier, P Kumar - Stem cell reviews and reports, 2022 - Springer
The physiological state of the tumor microenvironment (TME) plays a central role in cancer
development due to multiple universal features that transcend heterogeneity and niche …
development due to multiple universal features that transcend heterogeneity and niche …
[HTML][HTML] Galectin-1-mediated MET/AXL signaling enhances sorafenib resistance in hepatocellular carcinoma by escaping ferroptosis
TW Hsu, YH Su, HA Chen, PH Liao, SC Shen… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Sorafenib, a small-molecule inhibitor targeting several tyrosine kinase pathways, is the
standard treatment for advanced hepatocellular carcinoma (HCC). However, not all patients …
standard treatment for advanced hepatocellular carcinoma (HCC). However, not all patients …
[HTML][HTML] The complex network of transcription factors, immune checkpoint inhibitors and stemness features in colorectal cancer: A recent update
Cancer immunity is regulated by several mechanisms that include co-stimulatory and/or co-
inhibitory molecules known as immune checkpoints expressed by the immune cells. In …
inhibitory molecules known as immune checkpoints expressed by the immune cells. In …
[HTML][HTML] Cancer bioenergetics and tumor microenvironments—Enhancing chemotherapeutics and targeting resistant niches through nanosystems
Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …
[HTML][HTML] The role of Hedgehog signaling pathway in head and neck squamous cell carcinoma
P Cierpikowski, A Leszczyszyn, J Bar - Cells, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth leading malignancy
worldwide, with a poor prognosis and limited treatment options. Molecularly targeted …
worldwide, with a poor prognosis and limited treatment options. Molecularly targeted …