Over the last few years, progress has been made across the nanomedicine landscape, in
particular, the invention of contemporary nanostructures for cancer diagnosis and …

Cancer is a leading cause of death worldwide. In many cases, the treatment of the disease is
limited due to the metastasis of cells to distant locations of the body through the blood and …

The emerging concept of cancer stem cells (CSCs) as the key driver behind carcinogenesis,
progression, and diversity has displaced the prior model of a tumor composed of cells with …

Intra-tumor heterogeneity is now arguably one of the most-studied topics in tumor biology, as
it represents a major obstacle to effective cancer treatment. Since tumor cells are highly …

Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer
treatment strategies are evolving due to innate and acquired resistance capacity, governed …

The physiological state of the tumor microenvironment (TME) plays a central role in cancer
development due to multiple universal features that transcend heterogeneity and niche …

Sorafenib, a small-molecule inhibitor targeting several tyrosine kinase pathways, is the
standard treatment for advanced hepatocellular carcinoma (HCC). However, not all patients …

Cancer immunity is regulated by several mechanisms that include co-stimulatory and/or co-
inhibitory molecules known as immune checkpoints expressed by the immune cells. In …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

Head and neck squamous cell carcinoma (HNSCC) is the sixth leading malignancy
worldwide, with a poor prognosis and limited treatment options. Molecularly targeted …